{"id":4162,"date":"2024-02-25T09:25:00","date_gmt":"2024-02-25T09:25:00","guid":{"rendered":"http:\/\/biogroupvietnam-worldpress.local\/2025\/08\/18\/cell-enrichment-methodologies-using-cord-blood-as-a-source-automated-vs-manual\/"},"modified":"2025-09-29T13:59:55","modified_gmt":"2025-09-29T06:59:55","slug":"cac-phuong-phap-lam-giau-te-bao-co-nguon-goc-tu-mau-cuong-ron-phuong-phap-thu-cong-so-voi-quy-trinh-tu-dong","status":"publish","type":"post","link":"https:\/\/biogroupvietnam.com\/en\/new-products-technologies\/cell-enrichment-methodologies-using-cord-blood-as-a-source-automated-vs-manual\/","title":{"rendered":"Cell Enrichment Methodologies Using Cord Blood as a Source: Automated vs Manual"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/biogroupvietnam.com\/en\/new-products-technologies\/cell-enrichment-methodologies-using-cord-blood-as-a-source-automated-vs-manual\/#Overview_of_Cord_Blood_and_its_Uses\" >Overview of Cord Blood and its Uses<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/biogroupvietnam.com\/en\/new-products-technologies\/cell-enrichment-methodologies-using-cord-blood-as-a-source-automated-vs-manual\/#Cell_Processing_Using_Cord_Blood_and_The_Two_Options_for_Cell_Enrichment\" >Cell Processing Using Cord Blood and The Two Options for Cell Enrichment<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/biogroupvietnam.com\/en\/new-products-technologies\/cell-enrichment-methodologies-using-cord-blood-as-a-source-automated-vs-manual\/#The_Manual_Method\" >The Manual Method<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/biogroupvietnam.com\/en\/new-products-technologies\/cell-enrichment-methodologies-using-cord-blood-as-a-source-automated-vs-manual\/#The_Automated_Process\" >The Automated Process<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/biogroupvietnam.com\/en\/new-products-technologies\/cell-enrichment-methodologies-using-cord-blood-as-a-source-automated-vs-manual\/#TG_Offers_Solutions_for_Cord_Blood_Processing_and_Storage\" >TG Offers Solutions for Cord Blood Processing and Storage<\/a><\/li><\/ul><\/nav><\/div>\n<h2 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"Overview_of_Cord_Blood_and_its_Uses\"><\/span><strong>Overview of Cord Blood and its Uses<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p style=\"text-align: justify;\">Cord blood is blood found in the blood vessels of the placenta and the umbilical cord. It is collected after a baby is born and once the umbilical cord is cut, making it a safe procedure for both mother and baby. Cord blood is a good source of stem cells that form into blood cells, and can be used for transplantation in people who need regeneration of these blood-forming cells.<\/p>\n<p style=\"text-align: justify;\">Currently, the FDA has approved cord blood for use in hematopoietic stem cell transplantation procedures, which are those that affect a patient\u2019s blood forming system. Cord blood has been used to treat blood cancers such as leukemia and lymphoma, and has also been used for certain blood and immune system disorders, such as sickle cell disease.<\/p>\n<h2 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"Cell_Processing_Using_Cord_Blood_and_The_Two_Options_for_Cell_Enrichment\"><\/span><strong>Cell Processing Using Cord Blood and The Two Options for Cell Enrichment<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p style=\"text-align: justify;\">The goal of cord blood processing is to isolate and extract the maximum amount of valuable cells without contamination or damage. Preserving the highest quality and quantity of cells ensures they will be ready for future clinical use while minimizing the risk of complication.<\/p>\n<p style=\"text-align: justify;\">When it comes to the cell enrichment process, there are two options:<\/p>\n<ul>\n<li>\n<p style=\"text-align: justify;\">Manual Processing<\/p>\n<\/li>\n<li>\n<p style=\"text-align: justify;\">Automated Processing<\/p>\n<\/li>\n<\/ul>\n<h2 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"The_Manual_Method\"><\/span><strong>The Manual Method<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p style=\"text-align: justify;\">Manual processing is the most common cell processing method used by the majority of cell banks. Trained lab technicians process cells by hand, using a process called Hetastarch in manual processing bag sets. Research facilities, or those that want to use cells for research or manufacturing purposes may use a density gradient medium, such as Ficoll-Paque, to isolate cells from the blood. The Ficoll method was first used in 1964 by B\u00f6yum. &nbsp;Using this method, cell samples can contain only the good, white blood cells if left in a container at room temperature for approximately an hour.<\/p>\n<ul>\n<li>\n<p style=\"text-align: justify;\">Benefits of Manual Cell Processing: The biggest advantage of manual cell processing is that it is more cost effective. It is also better for processing the smallest family collections because the procedures can be customized as needed.<\/p>\n<\/li>\n<li>\n<p style=\"text-align: justify;\">Drawbacks: The greatest disadvantage of manual cell processing is that it is highly dependent on the lab technician\u2019s skills, which could lead to inconsistent results. It also leaves greater room for error, which is something that should be minimized at all costs in order for the cells to be viable for future use.<\/p>\n<\/li>\n<\/ul>\n<h2 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"The_Automated_Process\"><\/span><strong>The Automated Process<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p style=\"text-align: justify;\"><img fetchpriority=\"high\" decoding=\"async\" src=\"https:\/\/biogroupvietnam.com\/assets\/uploads\/image\/pxp-1000-system.jpg\" alt=\"\" width=\"300\" height=\"334\" \/>Automated cell processing is a less popular option, however using a highly sophisticated system, such as the PXP\u00ae-1000, offers many advantages.<\/p>\n<ul>\n<li>\n<p style=\"text-align: justify;\">Advantages of Automated Cell Processing: Fully automated cell processing has many advantages, including reducing the risk of contamination, increasing the consistency of the process and the results. Minimizing risk is of the utmost importance, as the goal of cell processing is to ensure the most efficient and safe results for a patient\u2019s use in the future.<\/p>\n<\/li>\n<li>\n<p style=\"text-align: justify;\">The PXP\u00ae-1000: The PXP\u00ae-1000 System is designed to provide a fast, automated, and reproducible separation of cord blood with minimal red blood cell contamination in a closed and sterile environment. By reducing red blood cell contamination, this fully automated, closed system provides a more pure cell enrichment. Using this system, scientists and medical professionals can be confident that they are providing their patients with the highest quality final product.<\/p>\n<\/li>\n<\/ul>\n<h2 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"TG_Offers_Solutions_for_Cord_Blood_Processing_and_Storage\"><\/span><strong>TG Offers Solutions for Cord Blood Processing and Storage<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p style=\"text-align: justify;\">ThermoGenesis Holdings Inc. (formerly Cesca Therapeutics Inc.), is a pioneer and market leader in the development and commercialization of automated cell processing technologies for the cell and gene therapy fields. We market a full suite of solutions for automated clinical biobanking, point-of-care applications and large-scale cell processing and manufacturing with a special emphasis on the emerging CAR-T immunotherapy market. We are committed to making the world a healthier place by creating innovative solutions for those in need.<\/p>\n<p style=\"text-align: justify;\">For more information, please contact our Sales team.<\/p>\n<p><i>(Thermogenesis \u2013 USA)<\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Overview of Cord Blood and its Uses Cord blood is blood found in the blood vessels of the placenta and the umbilical cord. It is collected after a baby is born and once the umbilical cord is cut, making it a safe procedure for both mother and baby. Cord blood is a good source of<\/p>\n<div class=\"klb-readmore post-buttons\"><a class=\"button rounded primary\" href=\"https:\/\/biogroupvietnam.com\/en\/new-products-technologies\/cell-enrichment-methodologies-using-cord-blood-as-a-source-automated-vs-manual\/\">Read More <i class=\"klbth-icon-right-arrow\"><\/i><\/a><\/div>\n","protected":false},"author":1,"featured_media":4489,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[17],"tags":[],"class_list":["post-4162","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-new-products-technologies"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cell Enrichment Methodologies Using Cord Blood as a Source: Automated vs Manual<\/title>\n<meta name=\"description\" content=\"Overview of Cord Blood and its Uses Cord blood is blood found in the blood vessels of the placenta and the umbilical cord. 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