{"id":4181,"date":"2024-02-25T09:51:00","date_gmt":"2024-02-25T09:51:00","guid":{"rendered":"http:\/\/biogroupvietnam-worldpress.local\/2025\/08\/18\/spectrophotometer-for-lab-room\/"},"modified":"2026-04-22T15:16:44","modified_gmt":"2026-04-22T08:16:44","slug":"may-do-quang-pho-cho-phong-lab","status":"publish","type":"post","link":"https:\/\/biogroupvietnam.com\/en\/blog\/spectrophotometer-for-lab-room\/","title":{"rendered":"3 tips to choosing the right spectrophotometer for lab"},"content":{"rendered":"<p><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">A spectrophotometer is a fundamental but essential device in many laboratories, commonly used to analyze nucleic acids, quantify proteins, and perform other optical measurements. However, not all models meet the specific requirements for each application.<\/span><\/p>\n<p><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">Based on new technological platforms and practical experience, this article summarizes three principles for selecting a spectrophotometer to help researchers and technical investors make accurate, effective, and long-term usage decisions.<\/span><\/p>\n<figure class=\"image\"><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter size-full wp-image-7207\" src=\"https:\/\/biogroupvietnam.com\/wp-content\/uploads\/2025\/09\/May-do-quang-pho-cho-phong-lab-EzDrop-1000-2.png\" alt=\"Spectrophotometer for lab room - EzDrop 1000&nbsp;\" width=\"2240\" height=\"1260\" srcset=\"https:\/\/biogroupvietnam.com\/wp-content\/uploads\/2025\/09\/May-do-quang-pho-cho-phong-lab-EzDrop-1000-2.png 2240w, https:\/\/biogroupvietnam.com\/wp-content\/uploads\/2025\/09\/May-do-quang-pho-cho-phong-lab-EzDrop-1000-2-300x169.png 300w, https:\/\/biogroupvietnam.com\/wp-content\/uploads\/2025\/09\/May-do-quang-pho-cho-phong-lab-EzDrop-1000-2-1024x576.png 1024w, https:\/\/biogroupvietnam.com\/wp-content\/uploads\/2025\/09\/May-do-quang-pho-cho-phong-lab-EzDrop-1000-2-768x432.png 768w\" sizes=\"(max-width: 2240px) 100vw, 2240px\" \/><figcaption><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\"><i>Spectrophotometer for lab &#8211; EzDrop 1000&nbsp;<\/i><\/span><\/figcaption><\/figure>\n<h2><strong><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 20pt;\">What are the applications of a spectrophotometer?<\/span><\/strong><\/h2>\n<p><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">A spectrophotometer is a tool used to perform qualitative and quantitative analyses effectively. It is widely applied in scientific fields and various industries such as medicine, materials, environment, chemistry, biology, and food.<\/span><\/p>\n<p><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">In biological laboratories, a spectrophotometer is commonly used for:<\/span><\/p>\n<ul>\n<li><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">Measuring and analyzing nucleic acid and protein samples, DNA\/RNA concentrations.<\/span><\/li>\n<li><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">Checking bacterial content in organisms.<\/span><\/li>\n<li><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">Determining if a solution contains a specific substance.<\/span><\/li>\n<\/ul>\n<p><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">Current spectrophotometer models on the market have been developed from traditional UV-Vis spectrophotometers with the following characteristics:<\/span><\/p>\n<ul>\n<li><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">A cuvette is required to hold the sample before placing it into the spectrophotometer.<\/span><\/li>\n<li><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">Use ultraviolet or tungsten light sources, which have a short lifespan and require at least half an hour of warm-up time before measurements.<\/span><\/li>\n<li><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">Need a minimum of 50\u03bcL of diluted sample in the cuvette, with a limited detection range, meaning they can only record absorbance values, not concentrations.<\/span><\/li>\n<\/ul>\n<p><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">Overall, these traditional spectrophotometers are significantly limited in advanced analytical applications.&nbsp;<\/span><\/p>\n<h2><strong><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 20pt;\">New generation microvolume spectrophotometers<\/span><\/strong><\/h2>\n<p><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">New models of microvolume spectrophotometers increase measurement efficiency with more optimized features:<\/span><\/p>\n<ul>\n<li><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">Use a xenon light source, which has a longer lifespan, is more stable, and allows immediate experimentation without pre-heating.<\/span><\/li>\n<li><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">Measure samples without using cuvettes, requiring only 1-2\u00b5L of sample to measure absorbance and concentration. This is why they are called microvolume spectrophotometers.<\/span><\/li>\n<li><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">Save costs due to the small sample volume, reducing the need for deionized water to clean cuvettes and minimizing consumables.<\/span><\/li>\n<li><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">Simplify the operation process: with microvolume spectrophotometers, cleaning the sample window with tissue paper after each measurement allows continuous sample measurements. This increases measurement efficiency and reduces contamination and user errors.<\/span><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">&nbsp;<\/span><\/li>\n<\/ul>\n<p><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">With these improvements, microvolume spectrophotometers are becoming the optimal choice for modern labs, which require both accuracy and efficiency while saving costs.<\/span><\/p>\n<h2><strong><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 20pt;\">Tips for choosing the right spectrophotometer<\/span><\/strong><\/h2>\n<p><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">There are three key tricks when surveying and choosing the right spectrophotometer:<\/span><\/p>\n<h3 style=\"text-align: justify;\"><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 16pt;\">Measurement efficiency of the spectrophotometer<\/span><\/h3>\n<p><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">Most spectrophotometers on the market provide results in 8-10 seconds, which is an improvement compared to traditional models (those using cuvettes).<\/span><\/p>\n<p><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">However, newer microvolume spectrophotometer models take only 3 seconds to provide results, improving measurement efficiency by 2-3 times compared to older models. This saves a significant amount of time in experiments and tests.<\/span><\/p>\n<h3><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 16pt;\">Accuracy of the spectrophotometer<\/span><\/h3>\n<p><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">Some spectrophotometer models on the market can achieve an error rate below 1%. This is because the sample window and disc are made from quartz glass with a hydrophobic nano-coating, which helps samples form droplets through cohesion and reduces light scattering.<\/span><\/p>\n<p><span style=\"background-color: transparent; color: #0e101a; font-family: Arial,sans-serif; font-size: 12pt;\">The light source supports the observation of the sample window and checks for air bubbles during the measurement process. This helps users detect air bubbles to ensure accurate and repeatable results.&nbsp;<\/span><\/p>\n<h3><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 16pt;\">Spectrophotometer calibration<\/span><\/h3>\n<p><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">There are two types of calibration for a spectrophotometer: light source calibration and optical path length calibration. The light source&#8217;s brightness decreases over time and should be calibrated every 1-2 years. Calibration can be done based on the manufacturer&#8217;s specifications, and users can adjust the machine themselves without factory calibration.<\/span><\/p>\n<p><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">The biggest issue with current spectrophotometers is difficulty calibrating the optical path length. Due to varying sample concentrations, electric motors adjust the optical path length, which affects the machine&#8217;s parameters and built-in formulas. The spectrophotometer needs recalibration every 3-6 months, depending on sample usage frequency.<\/span><\/p>\n<p><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">Choosing a spectrophotometer with a fixed optical path length solves this calibration issue. Users can select the appropriate optical path length based on sample concentration. For low dsDNA concentrations (e.g., 2-1500 ng\/\u00b5l), a longer optical path (0.5 mm) is used, whereas for higher concentrations (1000-20000 ng\/\u00b5l), a shorter path is applied.<\/span><\/p>\n<p><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">In addition to these key tricks, researchers should consider factors such as choosing reputable manufacturers and suppliers of spectrophotometers who offer timely support and expertise.<\/span><\/p>\n<p><a href=\"https:\/\/biogroupvietnam.com\/en\/blog\/comparative-performance-micro-volume-uv-vis-spectrophotometers-ezdrop-1000-nanodrop-one-nanodrop-2000-ds-11\/\"><em><strong>Learn more:<\/strong> <\/em><em>Comparative performance of Micro-Volume UV\/Vis Spectrophotometers EzDrop 1000, NanoDrop\u2122 One \/ NanoDrop\u2122 2000, DS-11<\/em><\/a><\/p>\n<h2><strong><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 20pt;\">Other considerations when choosing a spectrophotometer<\/span><\/strong><\/h2>\n<p><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">When purchasing a spectrophotometer, users should also consider specific spectrophotometer features, such as ease of operation, application expandability, and supplier support services. Most modern spectrophotometers include functions for determining concentration, quantifying nucleic acids, A280 protein, protein assays, and measuring cell optical density (OD 600).&nbsp;<\/span><\/p>\n<p><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">Researchers can install absorption settings, set formulas, and define tests for application expandability. Additionally, the best technical support services should be provided, such as:&nbsp;<\/span><\/p>\n<ul>\n<li><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">Prompt resolution of technical issues during spectrophotometer operation.&nbsp;<\/span><\/li>\n<li><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">Free warranty for device malfunctions not caused by the user.<\/span><\/li>\n<li><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">A 30-day trial, demo, and return policy if the spectrophotometer malfunctions due to a manufacturer defect.&nbsp;<\/span><\/li>\n<\/ul>\n<p><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">After purchasing the device, users often face additional calibration, consumables, and equipment maintenance costs.<\/span><a href=\"https:\/\/www.blue-raybio.com\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">&nbsp;<\/span><span style=\"background-color: transparent; color: #1155cc; font-family: Arial,sans-serif; font-size: 12pt;\">Blue-Ray Biotech<\/span><\/a><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\"> has developed the<\/span><a href=\"https:\/\/biogroupvietnam.com\/san-pham\/ezdrop-1000-micro-volume\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">&nbsp;<\/span><span style=\"background-color: transparent; color: #1155cc; font-family: Arial,sans-serif; font-size: 12pt;\">EzDrop 1000<\/span><\/a><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\"> microvolume spectrophotometer to reduce these issues, which meets all the selection criteria mentioned above. With features for quick nucleic acid and protein quantification in 3 seconds, the EzDrop spectrophotometer has become a valuable tool for laboratories.<\/span><\/p>\n<p><a href=\"https:\/\/www.blue-raybio.com\/en\/solution\/Nucleic-Acid-Testing-Solution\"><em><strong>Learn <\/strong><\/em><em><strong>m<\/strong><\/em><em><strong>ore: <\/strong><\/em><em>Nucleic Acid Testing Solution<\/em><\/a><br \/>\n<span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\"><br \/>\nBiogroup Vietnam is a strategic distributor partner of Blue-Ray Biotech. If you need support with spectrophotometers, we are always ready to answer any questions.<\/span><\/p>\n<p><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 13.999999999999998pt;\"> &nbsp;<strong>Contact us<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">Website:<\/span><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">&nbsp;<\/span><span style=\"background-color: transparent; color: #1155cc; font-family: Arial,sans-serif; font-size: 12pt;\">https:\/\/biogroupvietnam.com\/en\/contact-us<\/span><\/li>\n<li><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">Hotline: +84 963 621 421<\/span><\/li>\n<li><span style=\"background-color: transparent; color: #000000; font-family: Arial,sans-serif; font-size: 12pt;\">Email:&nbsp;<\/span><span style=\"background-color: transparent; color: #1155cc; font-family: Arial,sans-serif; font-size: 12pt;\">info@biogroupvietnam.com<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>A spectrophotometer is a fundamental but essential device in many laboratories, commonly used to analyze nucleic acids, quantify proteins, and perform other optical measurements. However, not all models meet the specific requirements for each application. Based on new technological platforms and practical experience, this article summarizes three principles for selecting a spectrophotometer to help researchers<\/p>\n<div class=\"klb-readmore post-buttons\"><a class=\"button rounded primary\" href=\"https:\/\/biogroupvietnam.com\/en\/blog\/spectrophotometer-for-lab-room\/\">Read More <i class=\"klbth-icon-right-arrow\"><\/i><\/a><\/div>\n","protected":false},"author":1,"featured_media":5955,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4181","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>3 tips to choosing the right spectrophotometer for lab<\/title>\n<meta name=\"description\" content=\"A spectrophotometer is a fundamental but essential device in many laboratories, commonly used to analyze nucleic acids, quantify proteins, and perform other optical measurements. 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