{"id":4156,"date":"2024-02-25T09:22:15","date_gmt":"2024-02-25T09:22:15","guid":{"rendered":"http:\/\/biogroupvietnam-worldpress.local\/2025\/08\/18\/nanoparticles-tumor-tracing-with-alliance-q9-system-with-a-chroma\/"},"modified":"2025-09-29T13:59:53","modified_gmt":"2025-09-29T06:59:53","slug":"theo-doi-khoi-u-bang-hat-nano-voi-he-thong-alliance-q9-voi-chroma","status":"publish","type":"post","link":"https:\/\/biogroupvietnam.com\/vi\/cong-nghe-san-pham-moi\/theo-doi-khoi-u-bang-hat-nano-voi-he-thong-alliance-q9-voi-chroma\/","title":{"rendered":"Theo d\u00f5i kh\u1ed1i u b\u1eb1ng h\u1ea1t nano v\u1edbi h\u1ec7 th\u1ed1ng Alliance Q9 (v\u1edbi Chroma)"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">M\u1ee5c l\u1ee5c<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/biogroupvietnam.com\/vi\/cong-nghe-san-pham-moi\/theo-doi-khoi-u-bang-hat-nano-voi-he-thong-alliance-q9-voi-chroma\/#Muc_tieu_va_muc_dich\" >M\u1ee5c ti\u00eau v\u00e0 m\u1ee5c \u0111\u00edch:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/biogroupvietnam.com\/vi\/cong-nghe-san-pham-moi\/theo-doi-khoi-u-bang-hat-nano-voi-he-thong-alliance-q9-voi-chroma\/#Mo_hinh_thu_nghiem\" >M\u00f4 h\u00ecnh th\u1eed nghi\u1ec7m:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/biogroupvietnam.com\/vi\/cong-nghe-san-pham-moi\/theo-doi-khoi-u-bang-hat-nano-voi-he-thong-alliance-q9-voi-chroma\/#Phuong_phap\" >Ph\u01b0\u01a1ng ph\u00e1p:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/biogroupvietnam.com\/vi\/cong-nghe-san-pham-moi\/theo-doi-khoi-u-bang-hat-nano-voi-he-thong-alliance-q9-voi-chroma\/#Ket_qua\" >K\u1ebft qu\u1ea3:<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Muc_tieu_va_muc_dich\"><\/span><strong>M\u1ee5c ti\u00eau v\u00e0 m\u1ee5c \u0111\u00edch<\/strong>:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li>\n<p style=\"text-align:justify\">M\u1ee5c ti\u00eau: th\u1ef1c hi\u1ec7n m\u1ed9t th\u00ed nghi\u1ec7m theo d\u00f5i kh\u1ed1i u b\u1eb1ng h\u1ea1t nano polytyrosine-ICG k\u00e9o d\u00e0i 48 gi\u1edd. Ch\u00fang t\u00f4i \u0111\u00e3 thi\u1ebft k\u1ebf m\u1ed9t lo\u1ea1i thu\u1ed1c nhu\u1ed9m hu\u1ef3nh quang \u0111\u01b0\u1ee3c g\u1eafn s\u1eb5n c\u00e1c h\u1ea1t nano, c\u00f3 th\u1ec3 li\u00ean k\u1ebft v\u1edbi c\u00e1c ch\u1ea5t \u0111\u1ed3ng v\u1ecb v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng t\u1ea3i thu\u1ed1c.<\/p>\n<\/li>\n<li>\n<p style=\"text-align:justify\">M\u1ee5c \u0111\u00edch c\u1ee7a nghi\u00ean c\u1ee9u l\u00e0 t\u1ea1o ra m\u1ed9t v\u1eadt li\u1ec7u th\u00edch h\u1ee3p m\u1edbi \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb. S\u1ef1 ph\u00e1t s\u00e1ng c\u1ee7a ICG s\u1ebd ch\u1ee9ng minh \u0111\u01b0\u1ee3c s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a n\u00f3 trong kh\u1ed1i u.<\/p>\n<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"Mo_hinh_thu_nghiem\"><\/span><strong>M\u00f4 h\u00ecnh th\u1eed nghi\u1ec7m<\/strong>:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>X\u00e2y d\u1ef1ng m\u00f4 h\u00ecnh kh\u1ed1i u 4T1 c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb chu\u1ed9t tr\u00ean chu\u1ed9t b\u1ea1ch t\u1ea1ng BALB\/c.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Phuong_phap\"><\/span><strong>Ph\u01b0\u01a1ng ph\u00e1p<\/strong>:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li>\n<p style=\"text-align:justify\">Sau khi kh\u1ed1i u c\u00f3 k\u00edch th\u01b0\u1edbc l\u00ean \u0111\u1ebfn 200 mm3, ti\u1ebfn h\u00e0nh ti\u00eam 200 \u03bcl thu\u1ed1c qua t\u0129nh m\u1ea1ch \u0111u\u00f4i. Li\u1ec1u l\u01b0\u1ee3ng thu\u1ed1c t\u01b0\u01a1ng \u0111\u01b0\u01a1ng kho\u1ea3ng 5 mg\/kg th\u1ec3 tr\u1ecdng.<\/p>\n<\/li>\n<li>\n<p style=\"text-align:justify\">Sau khi ti\u00eam, ch\u00fang t\u00f4i li\u00ean t\u1ee5c ph\u00e1t hi\u1ec7n c\u00e1c t\u00edn hi\u1ec7u hu\u1ef3nh quang v\u00e0 \u0111\u1ed3ng v\u1ecb sau c\u00e1c kho\u1ea3ng th\u1eddi gian 4h, 12h, 24h v\u00e0 48h.<\/p>\n<\/li>\n<li>\n<p style=\"text-align:justify\">ICG \u0111\u01b0\u1ee3c mua t\u1eeb C\u00f4ng ty J&amp;K Scientific.<\/p>\n<\/li>\n<li>\n<p style=\"text-align:justify\">H\u1ec7 th\u1ed1ng ch\u1ee5p \u1ea3nh \u0111\u1ed9ng v\u1eadt s\u1ed1ng ti\u00ean ti\u1ebfn <a href=\"https:\/\/biogroupvietnam.com\/vi\/products\/nghien-cuu-sinh-hoc\/chup-anh-gel\/alliance-q9-advanced.html\">Alliance Q9<\/a> l\u00e0 s\u1ea3n ph\u1ea9m c\u1ee7a C\u00f4ng ty Uvitec Anh Qu\u1ed1c Ltd.<\/p>\n<\/li>\n<li>\n<p style=\"text-align:justify\">H\u00ecnh \u1ea3nh n\u00e0y \u0111\u01b0\u1ee3c ch\u1ee5p qua k\u00eanh Chromapure IR780 nm, s\u1eed d\u1ee5ng b\u1ed9 l\u1ecdc d\u1ea3i h\u1eb9p F850. Chu\u1ed9t \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o v\u1ecb tr\u00ed c\u1ee7a Tray 3. Kh\u1ea9u \u0111\u1ed9 l\u00e0 F0.80 v\u00e0 th\u1eddi gian ph\u01a1i s\u00e1ng l\u00e0 600 mili gi\u00e2y v\u1edbi \u0111\u1ed9 ph\u00e2n gi\u1ea3i 4X4.<\/p>\n<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"Ket_qua\"><\/span><strong>K\u1ebft qu\u1ea3<\/strong>:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li>\n<p style=\"text-align:justify\">C\u00e1c v\u1eadt li\u1ec7u nano \u0111\u01b0\u1ee3c l\u00e0m gi\u00e0u trong kh\u1ed1i u d\u01b0\u1edbi da do hi\u1ec7u \u1ee9ng EPR.<\/p>\n<\/li>\n<li>\n<p style=\"text-align:justify\">C\u00e1c v\u1eadt li\u1ec7u nano \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a v\u00e0 th\u1ea3i tr\u1eeb qua th\u1eadn.<\/p>\n<\/li>\n<li>\n<p style=\"text-align:justify\">V\u00ec c\u00e1c t\u00edn hi\u1ec7u hu\u1ef3nh quang b\u1ecb ch\u1eb7n b\u1edfi c\u00e1c m\u00f4 c\u01a1 c\u1ee7a c\u01a1&nbsp;quan, n\u00ean c\u00e1c t\u00edn hi\u1ec7u c\u1ee7a gan v\u00e0 l\u00e1 l\u00e1ch \u0111\u01b0\u1ee3c th\u1ec3 hi\u1ec7n l\u00e0 t\u01b0\u01a1ng \u0111\u1ed1i th\u1ea5p.<\/p>\n<\/li>\n<\/ul>\n<p><img fetchpriority=\"high\" decoding=\"async\" src=\"https:\/\/biogroupvietnam.com\/assets\/uploads\/image\/picture2.png\" alt=\"\" width=\"284\" height=\"300\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>M\u1ee5c ti\u00eau v\u00e0 m\u1ee5c \u0111\u00edch: M\u1ee5c ti\u00eau: th\u1ef1c hi\u1ec7n m\u1ed9t th\u00ed nghi\u1ec7m theo d\u00f5i kh\u1ed1i u b\u1eb1ng h\u1ea1t nano polytyrosine-ICG k\u00e9o d\u00e0i 48 gi\u1edd. Ch\u00fang t\u00f4i \u0111\u00e3 thi\u1ebft k\u1ebf m\u1ed9t lo\u1ea1i thu\u1ed1c nhu\u1ed9m hu\u1ef3nh quang \u0111\u01b0\u1ee3c g\u1eafn s\u1eb5n c\u00e1c h\u1ea1t nano, c\u00f3 th\u1ec3 li\u00ean k\u1ebft v\u1edbi c\u00e1c ch\u1ea5t \u0111\u1ed3ng v\u1ecb v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng t\u1ea3i<\/p>\n<div class=\"klb-readmore post-buttons\"><a class=\"button rounded primary\" href=\"https:\/\/biogroupvietnam.com\/vi\/cong-nghe-san-pham-moi\/theo-doi-khoi-u-bang-hat-nano-voi-he-thong-alliance-q9-voi-chroma\/\">Read More <i class=\"klbth-icon-right-arrow\"><\/i><\/a><\/div>\n","protected":false},"author":1,"featured_media":5630,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[17],"tags":[],"class_list":["post-4156","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cong-nghe-san-pham-moi"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Theo d\u00f5i kh\u1ed1i u b\u1eb1ng h\u1ea1t nano v\u1edbi h\u1ec7 th\u1ed1ng Alliance Q9 (v\u1edbi Chroma)<\/title>\n<meta name=\"description\" content=\"M\u1ee5c \u0111\u00edch c\u1ee7a nghi\u00ean c\u1ee9u l\u00e0 t\u1ea1o ra m\u1ed9t v\u1eadt li\u1ec7u th\u00edch h\u1ee3p m\u1edbi \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb. 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