{"id":4186,"date":"2024-02-25T09:54:00","date_gmt":"2024-02-25T09:54:00","guid":{"rendered":"http:\/\/biogroupvietnam-worldpress.local\/2025\/08\/18\/immunotherapy-car-t-therapy-revolutionize-the-cancer-treatment\/"},"modified":"2025-09-29T13:59:59","modified_gmt":"2025-09-29T06:59:59","slug":"lieu-phap-car-t-cach-mang-hoa-dieu-tri-ung-thu","status":"publish","type":"post","link":"https:\/\/biogroupvietnam.com\/vi\/blog\/lieu-phap-car-t-cach-mang-hoa-dieu-tri-ung-thu\/","title":{"rendered":"Li\u1ec7u ph\u00e1p CAR-T C\u00e1ch M\u1ea1ng H\u00f3a \u0110i\u1ec1u Tr\u1ecb Ung Th\u01b0"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">M\u1ee5c l\u1ee5c<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/biogroupvietnam.com\/vi\/blog\/lieu-phap-car-t-cach-mang-hoa-dieu-tri-ung-thu\/#Lieu_phap_mien_dich_la_gi\" >Li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch l\u00e0 g\u00ec?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/biogroupvietnam.com\/vi\/blog\/lieu-phap-car-t-cach-mang-hoa-dieu-tri-ung-thu\/#Te_bao_mien_dich_va_lieu_phap_CAR-T_cuu_song_benh_nhan_ung_thu\" >T\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch v\u00e0 li\u1ec7u ph\u00e1p CAR-T c\u1ee9u s\u1ed1ng b\u1ec7nh nh\u00e2n ung th\u01b0<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/biogroupvietnam.com\/vi\/blog\/lieu-phap-car-t-cach-mang-hoa-dieu-tri-ung-thu\/#Tien_bo_cua_lieu_phap_te_bao_CAR-T_cho_den_nay\" >Ti\u1ebfn b\u1ed9 c\u1ee7a li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o CAR-T cho \u0111\u1ebfn nay<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/biogroupvietnam.com\/vi\/blog\/lieu-phap-car-t-cach-mang-hoa-dieu-tri-ung-thu\/#Co_nhung_loai_phuong_phap_dieu_tri_ung_thu_bang_lieu_phap_mien_dich_nao\" >C\u00f3 nh\u1eefng lo\u1ea1i ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0 b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch n\u00e0o?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/biogroupvietnam.com\/vi\/blog\/lieu-phap-car-t-cach-mang-hoa-dieu-tri-ung-thu\/#Nhung_loai_ung_thu_nao_co_the_duoc_dieu_tri_bang_lieu_phap_mien_dich\" >Nh\u1eefng lo\u1ea1i ung th\u01b0 n\u00e0o c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/biogroupvietnam.com\/vi\/blog\/lieu-phap-car-t-cach-mang-hoa-dieu-tri-ung-thu\/#Lieu_phap_te_bao_CAR-T_co_hieu_qua_khong\" >Li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o CAR-T c\u00f3 hi\u1ec7u qu\u1ea3 kh\u00f4ng?<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Lieu_phap_mien_dich_la_gi\"><\/span><strong>Li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch l\u00e0 g\u00ec?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>M\u1ed7i ng\u00e0y, h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u1ee7a c\u01a1 th\u1ec3 ch\u00fang ta l\u00e0m vi\u1ec7c ch\u0103m ch\u1ec9 \u0111\u1ec3 gi\u00fap ch\u00fang ta kh\u1ecfe m\u1ea1nh v\u00e0 c\u01b0\u1eddng tr\u00e1ng. N\u00f3 l\u00e0 m\u1ed9t m\u1ea1ng l\u01b0\u1edbi ph\u1ee9c t\u1ea1p g\u1ed3m c\u00e1c lo\u1ea1i t\u1ebf b\u00e0o m\u00e1u &amp; k\u00edch th\u00edch t\u1ed1 (blood cells &amp; hormones) kh\u00e1c nhau, t\u1ea5t c\u1ea3 \u0111\u1ec1u ho\u1ea1t \u0111\u1ed9ng song song \u0111\u1ec3 ng\u0103n ng\u1eeba nhi\u1ec5m tr\u00f9ng, lo\u1ea1i b\u1ecf c\u00e1c t\u1ebf b\u00e0o \u0111\u1ed9t bi\u1ebfn v\u00e0 ti\u00eau di\u1ec7t c\u00e1c m\u1ed1i \u0111e d\u1ecda ti\u1ec1m \u1ea9n \u0111\u1ed1i v\u1edbi c\u01a1 th\u1ec3 ch\u00fang ta. \u0110\u00f3 l\u00e0 s\u1ee9c m\u1ea1nh c\u1ee7a h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u1ee7a ch\u00ednh ch\u00fang ta m\u00e0 c\u00e1c chuy\u00ean gia y t\u1ebf \u0111ang c\u1ed1 g\u1eafng s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ung th\u01b0.<\/p>\n<p>Ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0 b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 gi\u00fap c\u01a1 th\u1ec3 ch\u1ed1ng l\u1ea1i v\u00e0 v\u01b0\u1ee3t qua m\u1ed9t s\u1ed1 lo\u1ea1i ung th\u01b0. Ch\u00fang l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3 cho c\u00e1c chuy\u00ean gia y t\u1ebf, nh\u01b0ng nhi\u1ec1u ng\u01b0\u1eddi kh\u00f4ng bi\u1ebft li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch l\u00e0 g\u00ec, n\u00f3 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 l\u00e0m g\u00ec ho\u1eb7c l\u00e0m th\u1ebf n\u00e0o h\u1ecd c\u00f3 th\u1ec3 gi\u00fap ti\u1ebfp c\u1eadn n\u00f3. H\u00e3y c\u00f9ng \u0111i\u1ec3m qua nh\u1eefng y\u1ebfu t\u1ed1 c\u1ea7n thi\u1ebft v\u00e0 c\u00e1ch <a target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/healthbanks.us\/\">HealthBanks<\/a> c\u00f3 th\u1ec3 tr\u1ee3 gi\u00fap.<\/p>\n<p>C\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0 b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch d\u1ef1a tr\u00ean s\u1ee9c m\u1ea1nh \u0111\u00e1ng kinh ng\u1ea1c c\u1ee7a h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u1ee7a ch\u00fang ta, v\u1ec1 c\u01a1 b\u1ea3n s\u1ebd l\u1ea5y c\u00e1c t\u1ebf b\u00e0o m\u00e1u kh\u1ecfe m\u1ea1nh c\u1ee7a b\u1ea1n v\u00e0 bi\u1ebfn ch\u00fang th\u00e0nh c\u00e1c t\u1ebf b\u00e0o si\u00eau n\u0103ng l\u1ef1c nh\u1eafm v\u00e0o ung th\u01b0. N\u00f3i chung, h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u1ee7a ch\u00fang ta ch\u1ed1ng l\u1ea1i c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 m\u00e0 n\u00f3 t\u00ecm th\u1ea5y trong c\u01a1 th\u1ec3, nh\u01b0ng ung th\u01b0 c\u00f3 m\u1ed9t s\u1ed1 c\u00e1ch \u0111\u1ec3 ch\u1ed1ng l\u1ea1i c\u00e1c cu\u1ed9c t\u1ea5n c\u00f4ng n\u00e0y. Ung th\u01b0 tr\u00e1nh h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch theo ba c\u00e1ch sau:<\/p>\n<ul>\n<li>C\u00e1c t\u1ebf b\u00e0o ung th\u01b0 tr\u1ea3i qua nh\u1eefng thay \u0111\u1ed5i di truy\u1ec1n khi\u1ebfn ch\u00fang \u00edt b\u1ecb h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch nh\u00ecn th\u1ea5y h\u01a1n.<\/li>\n<li>Ung th\u01b0 t\u1ea1o ra c\u00e1c protein tr\u00ean b\u1ec1 m\u1eb7t c\u1ee7a ch\u00fang \u0111\u1ec3 ng\u0103n ch\u1eb7n s\u1ef1 ph\u00e1t hi\u1ec7n c\u1ee7a c\u00e1c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch.<\/li>\n<li>C\u00e1c t\u1ebf b\u00e0o ung th\u01b0 s\u1ebd thay \u0111\u1ed5i c\u00e1c t\u1ebf b\u00e0o kh\u1ecfe m\u1ea1nh xung quanh kh\u1ed1i u \u0111\u1ec3 ch\u00fang can thi\u1ec7p v\u00e0o ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch c\u1ee7a c\u00e1c t\u1ebf b\u00e0o ung th\u01b0.<\/li>\n<\/ul>\n<p>Li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o CAR-T l\u00e0 m\u1ed9t h\u00ecnh th\u1ee9c tr\u1ecb li\u1ec7u mi\u1ec5n d\u1ecbch s\u1eed d\u1ee5ng c\u00e1c t\u1ebf b\u00e0o T t\u1eeb h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u1ee7a ch\u00ednh b\u1ec7nh nh\u00e2n \u0111\u1ec3 gi\u00fap h\u1ecd ch\u1ed1ng l\u1ea1i ung th\u01b0. Th\u00f4ng th\u01b0\u1eddng, m\u1ed9t m\u1eabu t\u1ebf b\u00e0o T c\u1ee7a b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c thu th\u1eadp t\u1eeb m\u00e1u c\u1ee7a h\u1ecd, sau \u0111\u00f3 \u0111\u01b0\u1ee3c s\u1eeda \u0111\u1ed5i \u0111\u1ec3 t\u1ea1o ra c\u00e1c c\u1ea5u tr\u00fac \u0111\u1eb7c bi\u1ec7t g\u1ecdi l\u00e0 th\u1ee5 th\u1ec3 kh\u00e1ng nguy\u00ean d\u1ea1ng kh\u1ea3m (CAR) tr\u00ean b\u1ec1 m\u1eb7t c\u1ee7a ch\u00fang. Khi c\u00e1c t\u1ebf b\u00e0o CAR-T n\u00e0y \u0111\u01b0\u1ee3c \u0111\u01b0a tr\u1edf l\u1ea1i b\u1ec7nh nh\u00e2n, c\u00e1c th\u1ee5 th\u1ec3 m\u1edbi cho ph\u00e9p c\u00e1c t\u1ebf b\u00e0o T b\u00e1m v\u00e0o c\u00e1c kh\u00e1ng nguy\u00ean c\u1ee5 th\u1ec3 tr\u00ean c\u00e1c t\u1ebf b\u00e0o kh\u1ed1i u c\u1ee7a b\u1ec7nh nh\u00e2n, sau \u0111\u00f3 c\u00e1c t\u1ebf b\u00e0o n\u00e0y s\u1ebd b\u1ecb h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u1ee7a c\u01a1 th\u1ec3 t\u1ea5n c\u00f4ng.<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" src=\"http:\/\/building-management-system.local\/uploads\/8mB4viXRV65UR54VtHqBWUf1LOV8HpyEw36I1cvo.png\" alt=\"\" width=\"496\" height=\"302\"><\/p>\n<h3><span class=\"ez-toc-section\" id=\"Te_bao_mien_dich_va_lieu_phap_CAR-T_cuu_song_benh_nhan_ung_thu\"><\/span><strong>T\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch v\u00e0 li\u1ec7u ph\u00e1p CAR-T c\u1ee9u s\u1ed1ng b\u1ec7nh nh\u00e2n ung th\u01b0<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>M\u1ed7i n\u0103m, h\u01a1n 580.000 ng\u01b0\u1eddi \u1edf Hoa K\u1ef3 ch\u1ebft v\u00ec ung th\u01b0, m\u1eb7c d\u00f9 \u0111\u00e3 \u0111\u01b0\u1ee3c ph\u1eabu thu\u1eadt, x\u1ea1 tr\u1ecb v\u00e0 h\u00f3a tr\u1ecb. V\u1edbi c\u00e1c li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch CAR-T mang t\u00ednh c\u00e1ch m\u1ea1ng m\u1edbi, cu\u1ed9c s\u1ed1ng c\u1ee7a m\u1ecdi ng\u01b0\u1eddi gi\u1edd \u0111\u00e2y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c c\u1ee9u b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng c\u00e1c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch c\u1ee7a ch\u00ednh b\u1ea1n, l\u00e0 m\u1ed9t v\u0169 kh\u00ed ch\u1ed1ng ung th\u01b0 m\u1ea1nh nh\u1ea5t \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn. Xem c\u00e2u chuy\u1ec7n v\u1ec1 c\u00e1ch \u0111i\u1ec1u tr\u1ecb th\u00e0nh c\u00f4ng c\u1ee7a Emily Whitehead \u0111\u00e3 d\u1eabn \u0111\u1ebfn s\u1ef1 ch\u1ea5p thu\u1eadn c\u1ee7a FDA \u0111\u1ed1i v\u1edbi hai li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o CAR-T.<\/p>\n<p>Emily Whitehead n\u1ed5i ti\u1ebfng trong \u0111i\u1ec1u tr\u1ecb ung th\u01b0 v\u1edbi c\u00e2u chuy\u1ec7n th\u00e0nh c\u00f4ng \u0111\u00e1ng kinh ng\u1ea1c c\u1ee7a m\u00ecnh. C\u00f4 \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc b\u1ec7nh ung th\u01b0, b\u1ec7nh b\u1ea1ch c\u1ea7u lymphoblastic c\u1ea5p t\u00ednh, khi m\u1edbi 5 tu\u1ed5i. T\u00ecnh tr\u1ea1ng c\u1ee7a c\u00f4 tr\u1edf n\u00ean t\u1ed3i t\u1ec7 h\u01a1n \u0111\u00e1ng k\u1ec3 sau khi \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n. Sau 1 \u0111\u1ee3t h\u00f3a tr\u1ecb th\u1ea5t b\u1ea1i, t\u00ecnh tr\u1ea1ng c\u1ee7a c\u00f4 tr\u1edf n\u00ean t\u1ed3i t\u1ec7 \u0111\u1ebfn m\u1ee9c kh\u00f4ng c\u00f2n \u0111\u1ee7 \u0111i\u1ec1u ki\u1ec7n \u0111\u1ec3 gh\u00e9p. M\u1ed9t tia hy v\u1ecdng \u0111\u00e3 xu\u1ea5t hi\u1ec7n v\u1edbi gia \u0111\u00ecnh khi FDA M\u1ef9 v\u00e0 c\u00e1c \u1ee7y ban kh\u00e1c cu\u1ed1i c\u00f9ng \u0111\u00e3 ph\u00ea duy\u1ec7t <a target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.chop.edu\/treatments\/car-t-cell-therapy-immunotherapy-b-cell-acute-lymphoblastic-leukemia\">th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng Giai \u0111o\u1ea1n 1 c\u1ee7a b\u1ec7nh vi\u1ec7n \u0111\u1ed1i v\u1edbi li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o CAR-T \u1edf tr\u1ebb em<\/a> v\u1edbi Emily tr\u1edf th\u00e0nh b\u1ec7nh nh\u00e2n nhi \u0111\u1ea7u ti\u00ean. 23 ng\u00e0y sau, c\u00e1c m\u1eabu t\u1ee7y x\u01b0\u01a1ng x\u00e1c nh\u1eadn cu\u1ed1i c\u00f9ng c\u00f4 \u1ea5y kh\u00f4ng c\u00f2n ung th\u01b0 v\u00e0 v\u1eabn duy tr\u00ec k\u1ec3 t\u1eeb \u0111\u00f3. T\u00ednh \u0111\u1ebfn n\u0103m 2022, c\u00f4 k\u1ef7 ni\u1ec7m 15 n\u0103m kh\u1ecfi b\u1ec7nh ung th\u01b0. Th\u00e0nh c\u00f4ng \u0111\u00e1ng kinh ng\u1ea1c c\u1ee7a c\u00f4 \u1ea5y v\u00e0 th\u00e0nh c\u00f4ng c\u1ee7a nh\u1eefng ng\u01b0\u1eddi kh\u00e1c \u0111ang m\u1edf \u0111\u01b0\u1eddng cho vi\u1ec7c c\u1ee9u s\u1ed1ng nhi\u1ec1u ng\u01b0\u1eddi th\u00f4ng qua li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o T CAR. <a target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/people.com\/health\/teen-is-cured-from-cancer-after-groundbreaking-therapy-10-years-ago-its-a-miracle-im-alive\/\">Nh\u1ea5n v\u00e0o \u0111\u00e2y<\/a> \u0111\u1ec3 \u0111\u1ecdc v\u1ec1 c\u00e2u chuy\u1ec7n c\u1ee7a Emily.<\/p>\n<p>Hi\u1ec7n t\u1ea1i, li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o CAR-T \u0111\u00e3 \u0111\u01b0\u1ee3c FDA M\u1ef9 ch\u1ea5p thu\u1eadn l\u00e0 ti\u00eau chu\u1ea9n ch\u0103m s\u00f3c \u0111\u1ed1i v\u1edbi m\u1ed9t s\u1ed1 d\u1ea1ng ung th\u01b0 h\u1ea1ch kh\u00f4ng Hodgkin (non-Hodgkin lymphoma) x\u00e2m l\u1ea5n, kh\u00f3 ch\u1eefa v\u00e0 cho nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh b\u1ea1ch c\u1ea7u nguy\u00ean b\u00e0o lympho (lymphoblastic leukemia) c\u1ea5p t\u00ednh t\u00e1i ph\u00e1t ho\u1eb7c kh\u00f3 \u0111i\u1ec1u tr\u1ecb. Li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o CAR-T \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 c\u00f3 hi\u1ec7u qu\u1ea3 cao trong vi\u1ec7c ch\u1ed1ng l\u1ea1i c\u00e1c b\u1ec7nh ung th\u01b0 n\u00e0y. <strong>C\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng \u0111\u00e3 cho th\u1ea5y k\u1ebft qu\u1ea3 r\u1ea5t h\u1ee9a h\u1eb9n \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n giai \u0111o\u1ea1n cu\u1ed1i c\u1ee7a b\u1ec7nh v\u1edbi kh\u1ea3 n\u0103ng ph\u1ee5c h\u1ed3i ho\u00e0n to\u00e0n l\u00ean \u0111\u1ebfn 92% \u1edf nh\u1eefng ng\u01b0\u1eddi m\u1eafc b\u1ec7nh b\u1ea1ch c\u1ea7u Lympho c\u1ea5p t\u00ednh. Ngo\u00e0i ra, c\u00f3 h\u01a1n 800 th\u1eed nghi\u1ec7m \u0111ang di\u1ec5n ra v\u1ec1 li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o CAR-T cho c\u00e1c d\u1ea1ng ung th\u01b0 m\u00e1u v\u00e0 kh\u1ed1i u r\u1eafn kh\u00e1c<\/strong>.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Tien_bo_cua_lieu_phap_te_bao_CAR-T_cho_den_nay\"><\/span><strong>Ti\u1ebfn b\u1ed9 c\u1ee7a li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o CAR-T cho \u0111\u1ebfn nay<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<ul>\n<li>Li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch t\u1ebf b\u00e0o CAR-T s\u1eed d\u1ee5ng c\u00e1c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch kh\u1ecfe m\u1ea1nh c\u1ee7a ch\u00ednh m\u1ed9t ng\u01b0\u1eddi \u0111\u01b0\u1ee3c s\u1eeda \u0111\u1ed5i trong ph\u00f2ng Lab \u0111\u1ea1t ti\u00eau chu\u1ea9n AABB (\u0111\u01b0\u1ee3c AABB c\u00f4ng nh\u1eadn) c\u1ee7a <a target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/healthbanks.us\/\">HealthBanks Biotech<\/a> \u0111\u1ec3 ch\u1ed1ng l\u1ea1i c\u00e1c t\u1ebf b\u00e0o ung th\u01b0.<\/li>\n<li>Hi\u1ec7n t\u1ea1i c\u00f3 8 li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o CAR-T \u0111\u01b0\u1ee3c FDA M\u1ef9 ch\u1ea5p thu\u1eadn cho \u0111\u1ebfn n\u0103m 2022 v\u00e0 \u0111ang c\u00f3 h\u00e0ng ngh\u00ecn li\u1ec7u ph\u00e1p \u0111ang \u0111\u01b0\u1ee3c tri\u1ec3n khai.<\/li>\n<li>Hai li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o CAR-T b\u00e1o c\u00e1o t\u1ef7 l\u1ec7 \u0111\u00e1p \u1ee9ng tr\u00ean 80% \u1edf nh\u00f3m b\u1ec7nh nh\u00e2n th\u1ea5t b\u1ea1i v\u1edbi \u0111i\u1ec1u tr\u1ecb h\u00f3a tr\u1ecb &amp; x\u1ea1 tr\u1ecb.<\/li>\n<li>H\u00e0ng ngh\u00ecn b\u1ec7nh nh\u00e2n ung th\u01b0 \u0111\u00e3 thuy\u00ean gi\u1ea3m sau khi \u0111i\u1ec1u tr\u1ecb b\u1eb1ng t\u1ebf b\u00e0o CAR-T. T\u1ef7 l\u1ec7 \u0111\u00e1p \u1ee9ng v\u1edbi li\u1ec7u ph\u00e1p l\u00e0 c\u1ef1c k\u1ef3 th\u00fa v\u1ecb!<\/li>\n<li>H\u00e0ng t\u1ef7 \u0111\u00f4 la \u0111ang t\u00e0i tr\u1ee3 cho h\u01a1n 800 th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng t\u1ebf b\u00e0o CAR-T, bao g\u1ed3m: \u0111ang tuy\u1ec3n d\u1ee5ng, \u0111\u0103ng k\u00fd, \u0111ang \u0111i\u1ec1u tr\u1ecb &amp; ho\u1eb7c \u0111\u00e3 ho\u00e0n th\u00e0nh tr\u00ean to\u00e0n th\u1ebf gi\u1edbi.<\/li>\n<li>V\u1edbi c\u00f4ng ngh\u1ec7 x\u1eed l\u00fd t\u1ebf b\u00e0o t\u1ef1 \u0111\u1ed9ng ti\u00ean ti\u1ebfn, ng\u00e0y nay c\u00f3 nhi\u1ec1u \u0111\u1ed9t ph\u00e1 h\u01a1n n\u1eefa \u0111ang \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u.<\/li>\n<\/ul>\n<h3><span class=\"ez-toc-section\" id=\"Co_nhung_loai_phuong_phap_dieu_tri_ung_thu_bang_lieu_phap_mien_dich_nao\"><\/span><strong>C\u00f3 nh\u1eefng lo\u1ea1i ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0 b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch n\u00e0o?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>C\u00f3 5 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0 b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch kh\u00e1c nhau \u0111\u01b0\u1ee3c c\u00e1c nh\u00e0 cung c\u1ea5p d\u1ecbch v\u1ee5 y t\u1ebf s\u1eed d\u1ee5ng nh\u01b0:<\/p>\n<ul>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf \u0111i\u1ec3m ki\u1ec3m so\u00e1t mi\u1ec5n d\u1ecbch (immune checkpoint inhibitors) l\u00e0 m\u1ed9t lo\u1ea1i d\u01b0\u1ee3c ph\u1ea9m ng\u0103n ch\u1eb7n c\u00e1c \u0111i\u1ec3m ki\u1ec3m so\u00e1t mi\u1ec5n d\u1ecbch. C\u00e1c \u0111i\u1ec3m ki\u1ec3m so\u00e1t n\u00e0y l\u00e0 m\u1ed9t ph\u1ea7n trong ph\u1ea3n \u1ee9ng c\u1ee7a h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u1ee7a b\u1ea1n \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o r\u1eb1ng n\u00f3 kh\u00f4ng \u0111i qu\u00e1 xa trong cu\u1ed9c t\u1ea5n c\u00f4ng c\u1ee7a n\u00f3. B\u1eb1ng c\u00e1ch ch\u1eb7n c\u00e1c \u0111i\u1ec3m ki\u1ec3m so\u00e1t n\u00e0y, c\u01a1 th\u1ec3 c\u00f3 th\u1ec3 t\u1ea5n c\u00f4ng m\u1ea1nh m\u1ebd h\u01a1n.<\/li>\n<li>Kh\u00e1ng th\u1ec3 \u0111\u01a1n d\u00f2ng l\u00e0 c\u00e1c protein \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf \u0111\u1ec3 li\u00ean k\u1ebft v\u1edbi c\u00e1c m\u1ee5c ti\u00eau c\u1ee5 th\u1ec3 tr\u00ean t\u1ebf b\u00e0o ung th\u01b0. \u0110i\u1ec1u n\u00e0y l\u00e0m cho c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 d\u1ec5 nh\u1eadn di\u1ec7n h\u01a1n \u0111\u1ed1i v\u1edbi h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch, n\u00ean n\u00f3 s\u1ebd t\u1ea5n c\u00f4ng m\u1ea1nh m\u1ebd h\u01a1n. \u0110\u00f4i khi ch\u00fang \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 \u201ctherapeutic antibodies\u201d.<\/li>\n<li>V\u1eafc xin \u0111i\u1ec1u tr\u1ecb cho li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch kh\u00e1c v\u1edbi v\u1eafc xin ch\u00fang ta d\u00f9ng \u0111\u1ec3 ph\u00f2ng b\u1ec7nh. V\u1edbi v\u1eafc-xin ung th\u01b0 tr\u1ecb li\u1ec7u mi\u1ec5n d\u1ecbch, h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u1ee7a b\u1ea1n \u0111\u01b0\u1ee3c t\u0103ng c\u01b0\u1eddng \u0111\u1ec3 ph\u1ea3n \u1ee9ng t\u1ed1t h\u01a1n v\u1edbi b\u1ec7nh ung th\u01b0 v\u00e0 l\u00e0m vi\u1ec7c t\u00edch c\u1ef1c h\u01a1n \u0111\u1ec3 ch\u1ed1ng l\u1ea1i n\u00f3.<\/li>\n<li>C\u00e1c ch\u1ea5t \u0111i\u1ec1u bi\u1ebfn h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch (immune system modulators) t\u0103ng c\u01b0\u1eddng ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch c\u1ee7a c\u01a1 th\u1ec3 ch\u1ed1ng l\u1ea1i b\u1ec7nh ung th\u01b0. T\u00f9y thu\u1ed9c v\u00e0o c\u00e1ch ti\u1ebfp c\u1eadn, c\u00e1c b\u1ed9 \u0111i\u1ec1u bi\u1ebfn s\u1ebd \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1c b\u1ed9 ph\u1eadn c\u1ee5 th\u1ec3 c\u1ee7a h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch ho\u1eb7c to\u00e0n b\u1ed9 h\u1ec7 th\u1ed1ng c\u1ee7a b\u1ea1n n\u00f3i chung.<\/li>\n<li>M\u1ed9t trong nh\u1eefng lo\u1ea1i th\u1ee7 thu\u1eadt \u0111i\u1ec1u tr\u1ecb ung th\u01b0 b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch th\u00fa v\u1ecb v\u00e0 h\u1ea5p d\u1eabn nh\u1ea5t hi\u1ec7n c\u00f3 l\u00e0 li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o CAR-T. \u0110\u1ed1i v\u1edbi ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u00e0y, c\u00e1c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch \u0111\u01b0\u1ee3c l\u1ea5y t\u1eeb kh\u1ed1i u c\u1ee7a b\u1ec7nh nh\u00e2n v\u00e0 nh\u1eefng t\u1ebf b\u00e0o ho\u1ea1t \u0111\u1ed9ng t\u00edch c\u1ef1c nh\u1ea5t trong cu\u1ed9c chi\u1ebfn ch\u1ed1ng ung th\u01b0 c\u1ee7a b\u1ec7nh nh\u00e2n s\u1ebd b\u1ecb c\u00f4 l\u1eadp. C\u00e1c t\u1ebf b\u00e0o n\u00e0y sau \u0111\u00f3 \u0111\u01b0\u1ee3c s\u1eeda \u0111\u1ed5i \u0111\u1ec3 hi\u1ec7u qu\u1ea3 h\u01a1n, \u0111\u01b0\u1ee3c nu\u00f4i c\u1ea5y\/ t\u0103ng sinh t\u1ea1o s\u1ed1 l\u01b0\u1ee3ng l\u1edbn t\u1ebf b\u00e0o CAR-T v\u00e0 sau \u0111\u00f3 \u0111\u01b0\u1ee3c \u0111\u01b0a tr\u1edf l\u1ea1i c\u01a1 th\u1ec3 c\u1ee7a b\u1ec7nh nh\u00e2n th\u00f4ng qua ti\u00eam.<\/li>\n<\/ul>\n<h3><span class=\"ez-toc-section\" id=\"Nhung_loai_ung_thu_nao_co_the_duoc_dieu_tri_bang_lieu_phap_mien_dich\"><\/span><strong>Nh\u1eefng lo\u1ea1i ung th\u01b0 n\u00e0o c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Nhi\u1ec1u lo\u1ea1i ung th\u01b0 kh\u00e1c nhau c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng c\u00e1c th\u1ee7 thu\u1eadt \u0111i\u1ec1u tr\u1ecb ung th\u01b0 b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch. C\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb CAR-T hi\u1ec7n \u0111\u00e3 \u0111\u01b0\u1ee3c c\u01a1 quan FDA M\u1ef9 ch\u1ea5p thu\u1eadn \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb m\u1ed9t s\u1ed1 d\u1ea1ng ung th\u01b0 h\u1ea1ch kh\u00f4ng Hodgkin (non-Hodgkin lymphoma) kh\u00f3 ch\u1eefa &amp; cho nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh b\u1ea1ch c\u1ea7u lymphoblastic (lymphocytic leukemia) c\u1ea5p t\u00ednh t\u00e1i ph\u00e1t ho\u1eb7c kh\u00f3 \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>\u0110i\u1ec1u \u0111\u00f3 n\u00f3i r\u1eb1ng, m\u1ed9t trong nh\u1eefng l\u1ee3i \u00edch c\u1ee7a vi\u1ec7c s\u1eed d\u1ee5ng d\u1ecbch v\u1ee5 ng\u00e2n h\u00e0ng l\u00e0 b\u1ea1n c\u00f3 th\u1ec3 <strong>l\u01b0u tr\u1eef c\u00e1c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch c\u1ee7a m\u00ecnh \u0111\u1ec3 s\u1eed d\u1ee5ng trong c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb v\u1eabn \u0111ang \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n.<\/strong> V\u00ec li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch l\u00e0 m\u1ed9t chi\u1ebfn l\u01b0\u1ee3c \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh trong nhi\u1ec1u lo\u1ea1i ung th\u01b0, ch\u00fang t\u00f4i bi\u1ebft r\u1eb1ng vai tr\u00f2 c\u1ee7a n\u00f3 s\u1ebd \u0111\u01b0\u1ee3c m\u1edf r\u1ed9ng khi c\u00f4ng ngh\u1ec7 m\u1edbi ph\u00e1t tri\u1ec3n. Trong nh\u1eefng n\u0103m v\u00e0 th\u1eadp k\u1ef7 t\u1edbi, n\u00f3 c\u00f3 th\u1ec3 s\u1ebd \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng cho nhi\u1ec1u lo\u1ea1i ung th\u01b0 kh\u00e1c ngo\u00e0i ung th\u01b0 h\u1ea1ch kh\u00f4ng Hodgkin v\u00e0 b\u1ec7nh b\u1ea1ch c\u1ea7u lymphoblastic c\u1ea5p t\u00ednh.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Lieu_phap_te_bao_CAR-T_co_hieu_qua_khong\"><\/span><strong>Li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o CAR-T c\u00f3 hi\u1ec7u qu\u1ea3 kh\u00f4ng?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u0110\u00e3 c\u00f3 m\u1ed9t s\u1ed1 k\u1ebft qu\u1ea3 v\u00f4 c\u00f9ng h\u1ee9a h\u1eb9n trong c\u00e1c th\u1eed nghi\u1ec7m v\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch t\u1ebf b\u00e0o CAR-T. \u0110\u1ed1i v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh b\u1ea1ch c\u1ea7u lympho c\u1ea5p t\u00ednh, c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng cho th\u1ea5y t\u1ef7 l\u1ec7 h\u1ed3i ph\u1ee5c ho\u00e0n to\u00e0n l\u00ean t\u1edbi 92%. C\u00e1c nghi\u00ean c\u1ee9u kh\u00e1c \u0111\u00e3 b\u00e1o c\u00e1o t\u1ef7 l\u1ec7 \u0111\u00e1p \u1ee9ng tr\u00ean 80% \u0111\u1ed1i v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n th\u1ea5t b\u1ea1i trong \u0111i\u1ec1u tr\u1ecb h\u00f3a tr\u1ecb v\u00e0 x\u1ea1 tr\u1ecb. \u0110\u00e2y l\u00e0 k\u1ebft qu\u1ea3 \u0111\u1ea7u ti\u00ean trong s\u1ed1 h\u01a1n 800 th\u1eed nghi\u1ec7m hi\u1ec7n \u0111ang di\u1ec5n ra v\u1edbi li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0 b\u1eb1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch CAR-T.<\/p>\n<p><i>Ngu\u1ed3n t\u00e0i li\u1ec7u tham kh\u1ea3o: Thermogenesis (USA) &amp; HealthBanks Biotech (USA).<\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch l\u00e0 g\u00ec? M\u1ed7i ng\u00e0y, h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u1ee7a c\u01a1 th\u1ec3 ch\u00fang ta l\u00e0m vi\u1ec7c ch\u0103m ch\u1ec9 \u0111\u1ec3 gi\u00fap ch\u00fang ta kh\u1ecfe m\u1ea1nh v\u00e0 c\u01b0\u1eddng tr\u00e1ng. N\u00f3 l\u00e0 m\u1ed9t m\u1ea1ng l\u01b0\u1edbi ph\u1ee9c t\u1ea1p g\u1ed3m c\u00e1c lo\u1ea1i t\u1ebf b\u00e0o m\u00e1u &amp; k\u00edch th\u00edch t\u1ed1 (blood cells &amp; hormones) kh\u00e1c nhau, t\u1ea5t c\u1ea3<\/p>\n<div class=\"klb-readmore post-buttons\"><a class=\"button rounded primary\" href=\"https:\/\/biogroupvietnam.com\/vi\/blog\/lieu-phap-car-t-cach-mang-hoa-dieu-tri-ung-thu\/\">Read More <i class=\"klbth-icon-right-arrow\"><\/i><\/a><\/div>\n","protected":false},"author":1,"featured_media":5648,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4186","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Li\u1ec7u Ph\u00e1p Mi\u1ec5n D\u1ecbch - 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