{"id":4219,"date":"2024-02-25T10:14:22","date_gmt":"2024-02-25T10:14:22","guid":{"rendered":"http:\/\/biogroupvietnam-worldpress.local\/2025\/08\/18\/what-are-the-pros-and-cons-of-the-various-packaging-systems\/"},"modified":"2026-01-07T14:03:01","modified_gmt":"2026-01-07T07:03:01","slug":"uu-va-nhuoc-diem-cua-cac-vat-chua-mau-khac-nhau-la-gi","status":"publish","type":"post","link":"https:\/\/biogroupvietnam.com\/vi\/blog\/uu-va-nhuoc-diem-cua-cac-vat-chua-mau-khac-nhau-la-gi\/","title":{"rendered":"\u01afu v\u00e0 nh\u01b0\u1ee3c \u0111i\u1ec3m c\u1ee7a c\u00e1c v\u1eadt ch\u1ee9a m\u1eabu kh\u00e1c nhau l\u00e0 g\u00ec?"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">M\u1ee5c l\u1ee5c<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/biogroupvietnam.com\/vi\/blog\/uu-va-nhuoc-diem-cua-cac-vat-chua-mau-khac-nhau-la-gi\/#Uu_va_nhuoc_diem_cua_cac_vat_chua_mau_sinh_hoc_khac_nhau\" >\u01afu v\u00e0 nh\u01b0\u1ee3c \u0111i\u1ec3m c\u1ee7a c\u00e1c v\u1eadt ch\u1ee9a m\u1eabu sinh h\u1ecdc kh\u00e1c nhau<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/biogroupvietnam.com\/vi\/blog\/uu-va-nhuoc-diem-cua-cac-vat-chua-mau-khac-nhau-la-gi\/#Cong_tru_mau_truyen_thong\" >C\u1ecdng tr\u1eef m\u1eabu (truy\u1ec1n th\u1ed1ng)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/biogroupvietnam.com\/vi\/blog\/uu-va-nhuoc-diem-cua-cac-vat-chua-mau-khac-nhau-la-gi\/#Cong_tru_mau_bao_mat_cao\" >C\u1ecdng tr\u1eef m\u1eabu (b\u1ea3o m\u1eadt cao)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/biogroupvietnam.com\/vi\/blog\/uu-va-nhuoc-diem-cua-cac-vat-chua-mau-khac-nhau-la-gi\/#Ong_vial_dong_lanh\" >\u1ed0ng vial \u0111\u00f4ng l\u1ea1nh<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/biogroupvietnam.com\/vi\/blog\/uu-va-nhuoc-diem-cua-cac-vat-chua-mau-khac-nhau-la-gi\/#Ong_ampoule_thuy_tinh\" >\u1ed0ng ampoule th\u1ee7y tinh<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/biogroupvietnam.com\/vi\/blog\/uu-va-nhuoc-diem-cua-cac-vat-chua-mau-khac-nhau-la-gi\/#Nen_su_dung_cong_tru_mau_thay_vi_cryovial\" >N\u00ean s\u1eed d\u1ee5ng c\u1ecdng tr\u1eef m\u1eabu thay v\u00ec cryovial?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/biogroupvietnam.com\/vi\/blog\/uu-va-nhuoc-diem-cua-cac-vat-chua-mau-khac-nhau-la-gi\/#Nguon_tham_khao\" >Ngu\u1ed3n tham kh\u1ea3o<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Uu_va_nhuoc_diem_cua_cac_vat_chua_mau_sinh_hoc_khac_nhau\"><\/span>\u01afu v\u00e0 nh\u01b0\u1ee3c \u0111i\u1ec3m c\u1ee7a c\u00e1c v\u1eadt ch\u1ee9a m\u1eabu sinh h\u1ecdc kh\u00e1c nhau<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3><span class=\"ez-toc-section\" id=\"Cong_tru_mau_truyen_thong\"><\/span>C\u1ecdng tr\u1eef m\u1eabu (truy\u1ec1n th\u1ed1ng)<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>C\u1ecdng tr\u1eef m\u1eabu b\u1eb1ng nh\u1ef1a (\u0111\u00f4i khi c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 &#8220;c\u1ecdng tr\u1eef m\u1eabu Ph\u00e1p&#8221; ho\u1eb7c &#8220;paillettes&#8221;) \u0111\u01b0\u1ee3c Robert Cassou gi\u1edbi thi\u1ec7u l\u1ea7n \u0111\u1ea7u ti\u00ean v\u00e0o n\u0103m 1963 [Cassou, 1964]. \u00d4ng \u0111\u00e3 th\u00e0nh l\u1eadp c\u00f4ng ty Instruments de M\u00e9dicine V\u00e9t\u00e9rinaire hay IMV c\u00f3 tr\u1ee5 s\u1edf t\u1ea1i L\u2019Aigle (Ph\u00e1p) \u0111\u1ec3 th\u01b0\u01a1ng m\u1ea1i h\u00f3a c\u00f4ng ngh\u1ec7 n\u00e0y. C\u1ecdng tr\u1eef m\u1eabu ban \u0111\u1ea7u \u0111\u01b0\u1ee3c l\u00e0m t\u1eeb polyvinyl clorua (PVC) v\u00e0 sau \u0111\u00f3 l\u00e0 polyethylene terephthalate glycol (PETG). C\u1ecdng tr\u1eef m\u1eabu PVC \u0111\u00e3 b\u1ecb ng\u1eebng s\u1ea3n xu\u1ea5t v\u00e0o n\u0103m 1998 v\u00ec ch\u00fang kh\u00f4ng th\u1ec3 kh\u1eed tr\u00f9ng b\u1eb1ng chi\u1ebfu x\u1ea1 m\u00e0 kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn t\u00ednh to\u00e0n v\u1eb9n c\u01a1 h\u1ecdc c\u1ee7a ch\u00fang. C\u00e1c c\u00f4ng ty kh\u00e1c c\u0169ng \u0111\u00e3 s\u1ea3n xu\u1ea5t c\u00e1c s\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 nh\u01b0 paillettes c\u1ee7a Cassou.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Cong_tru_mau_bao_mat_cao\"><\/span>C\u1ecdng tr\u1eef m\u1eabu (b\u1ea3o m\u1eadt cao)<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>C\u1ecdng tr\u1eef m\u1eabu l\u00e0m t\u1eeb nh\u1ef1a ionomeric \u0111\u1eb7c bi\u1ec7t \u0111\u00e3 \u0111\u01b0\u1ee3c gi\u1edbi thi\u1ec7u v\u00e0o n\u0103m 1992 cho c\u00e1c \u1ee9ng d\u1ee5ng \u0111\u1eb7c bi\u1ec7t \u0111\u00f2i h\u1ecfi ti\u00eau chu\u1ea9n cao h\u01a1n v\u1ec1 t\u00ednh to\u00e0n v\u1eb9n c\u01a1 h\u1ecdc v\u00e0 ki\u1ec3m so\u00e1t sinh h\u1ecdc so v\u1edbi c\u00e1c lo\u1ea1i c\u1ecdng tr\u1eef m\u1eabu truy\u1ec1n th\u1ed1ng. Nh\u1eefng &#8220;c\u1ecdng tr\u1eef m\u1eabu b\u1ea3o m\u1eadt cao&#8221; n\u00e0y \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t v\u00e0 ph\u00e2n ph\u1ed1i \u0111\u1ed9c quy\u1ec1n b\u1edfi c\u00f4ng ty y t\u1ebf con c\u1ee7a IMV c\u00f3 t\u00ean l\u00e0 Cryo Bio System (Paris, Ph\u00e1p) \u0111\u1ec3 s\u1eed d\u1ee5ng trong h\u1ed7 tr\u1ee3 sinh s\u1ea3n \u1edf ng\u01b0\u1eddi v\u00e0 c\u00e1c l\u0129nh v\u1ef1c \u1ee9ng d\u1ee5ng kh\u00e1c. Nh\u1eefng c\u1ecdng tr\u1eef m\u1eabu CBS\u2122 High Security n\u00e0y th\u01b0\u1eddng \u0111\u01b0\u1ee3c g\u1ecdi \u0111\u01a1n gi\u1ea3n l\u00e0 &#8220;c\u1ecdng tr\u1eef m\u1eabu CBS\u2122&#8221;, nh\u01b0ng kh\u00f4ng \u0111\u01b0\u1ee3c nh\u1ea7m l\u1eabn v\u1edbi nh\u1eefng c\u1ecdng tr\u1eef m\u1eabu l\u00e0m t\u1eeb PETG kh\u00e1c m\u00e0 c\u00f4ng ty c\u0169ng b\u00e1n.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Ong_vial_dong_lanh\"><\/span>\u1ed0ng vial \u0111\u00f4ng l\u1ea1nh<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u1ed0ng vial b\u1eb1ng nh\u1ef1a c\u00f3 n\u1eafp v\u1eb7n ho\u1eb7c &#8220;cryovials&#8221; \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong ng\u00e2n h\u00e0ng l\u01b0u tr\u1eef tinh tr\u00f9ng, tr\u1ee9ng, v\u00e0 ph\u00f4i ng\u01b0\u1eddi th\u01b0\u1eddng l\u00e0 d\u00f2ng s\u1ea3n ph\u1ea9m NUNC\u2122 CryoTube\u00ae (Nunc A\/S, Roskilde, \u0110an M\u1ea1ch v\u00e0 Nalge Nunc International, Naperville, IL, M\u1ef9) \u0111\u01b0\u1ee3c l\u00e0m t\u1eeb polypropylene v\u1edbi n\u1eafp v\u1eb7n b\u1eb1ng polypropylen ho\u1eb7c polyetylen. C\u00e1c s\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 c\u0169ng c\u00f3 s\u1eb5n t\u1eeb c\u00e1c nh\u00e0 s\u1ea3n xu\u1ea5t kh\u00e1c nh\u01b0ng \u0111\u00e3 c\u00f3 b\u00e1o c\u00e1o giai tho\u1ea1i v\u1ec1 m\u1ee9c \u0111\u1ed9 nhi\u1ec5m n\u1ed9i \u0111\u1ed9c t\u1ed1 kh\u00e1c nhau c\u1ee7a m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m thay th\u1ebf n\u00e0y.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Ong_ampoule_thuy_tinh\"><\/span>\u1ed0ng ampoule th\u1ee7y tinh<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Nh\u1eefng \u1ed1ng n\u00e0y \u0111\u00e3 kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn kh\u00edch trong nhi\u1ec1u n\u0103m v\u00ec l\u00fd do an to\u00e0n do t\u00ednh d\u1ec5 v\u1ee1 c\u1ee7a ch\u00fang.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Nen_su_dung_cong_tru_mau_thay_vi_cryovial\"><\/span>N\u00ean s\u1eed d\u1ee5ng c\u1ecdng tr\u1eef m\u1eabu thay v\u00ec cryovial?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>C\u00e1c kh\u00eda c\u1ea1nh v\u1ec1 l\u1ecbch s\u1eed v\u00e0 s\u1edf th\u00edch c\u00e1 nh\u00e2n s\u1ebd kh\u00f4ng \u0111\u01b0\u1ee3c xem x\u00e9t \u1edf \u0111\u00e2y. Tuy nhi\u00ean, c\u00e1c l\u1eadp lu\u1eadn k\u1ef9 thu\u1eadt trong cu\u1ed9c tranh lu\u1eadn v\u1ec1 c\u1ecdng tr\u1eef m\u1eabu v\u00e0 cryovial li\u00ean quan \u0111\u1ebfn c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 t\u1ed1c \u0111\u1ed9 l\u00e0m m\u00e1t v\u00e0 l\u00e0m n\u00f3ng hi\u1ec7u qu\u1ea3 m\u00e0 c\u00e1c m\u1eabu \u0111\u01b0\u1ee3c l\u01b0u tr\u1eef trong c\u00e1c v\u1eadt ch\u1ee9a c\u00f3 b\u00e1n k\u00ednh kh\u00e1c nhau g\u1eb7p ph\u1ea3i, \u0111\u1ed9 d\u1ec5 v\u1ee1 c\u01a1 h\u1ecdc c\u1ee7a c\u00e1c v\u1eadt ch\u1ee9a kh\u00e1c nhau \u1edf nhi\u1ec7t \u0111\u1ed9 nit\u01a1 l\u1ecfng (t\u1ee9c l\u00e0 -196\u00b0C) , kh\u1ea3 n\u0103ng b\u1ecbt k\u00edn ho\u1eb7c r\u00f2 r\u1ec9 hi\u1ec7u qu\u1ea3 v\u00e0 ki\u1ec3m so\u00e1t sinh h\u1ecdc c\u1ee7a ch\u00fang. Nh\u1eefng v\u1ea5n \u0111\u1ec1 n\u00e0y c\u00f3 m\u1ed1i li\u00ean h\u1ec7 ch\u1eb7t ch\u1ebd v\u1edbi nhau v\u00ec ch\u00fang \u0111\u1ec1u b\u1ecb chi ph\u1ed1i b\u1edfi c\u00e1c \u0111\u1eb7c t\u00ednh v\u1eadt l\u00fd c\u1ee7a v\u1eadt ch\u1ee9a m\u1eabu. M\u1eb7c d\u00f9 c\u00e1c nghi\u00ean c\u1ee9u so s\u00e1nh tr\u1ef1c ti\u1ebfp kh\u1ea3 n\u0103ng s\u1ed1ng s\u00f3t trong \u0111i\u1ec1u ki\u1ec7n l\u1ea1nh c\u1ee7a giao t\u1eed ng\u01b0\u1eddi v\u00e0 ph\u00f4i trong c\u00e1c v\u1eadt ch\u1ee9a m\u1eabu kh\u00e1c nhau ch\u01b0a \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n, nh\u01b0ng Whittingham \u0111\u00e3 b\u00e1o c\u00e1o r\u1eb1ng ph\u00f4i chu\u1ed9t 8 t\u1ebf b\u00e0o \u0111\u00f4ng l\u1ea1nh trong \u1ed1ng \u0111\u00f4ng l\u1ea1nh b\u1eb1ng nh\u1ef1a cho th\u1ea5y t\u1ef7 l\u1ec7 s\u1ed1ng s\u00f3t trong \u0111i\u1ec1u ki\u1ec7n l\u1ea1nh v\u00e0 t\u1ed1c \u0111\u1ed9 ph\u00e1t tri\u1ec3n ph\u00f4i nang sau tan b\u0103ng th\u1ea5p h\u01a1n \u0111\u00e1ng k\u1ec3 so v\u1edbi c\u1ecdng tr\u1eef ph\u00f4i. [McLaughlin et al., 1999 ho\u1eb7c Wood, 1999]. Ngo\u00e0i ra, g\u1ea7n 40 n\u0103m qua, ng\u01b0\u1eddi ta \u0111\u00e3 bi\u1ebft r\u1eb1ng tinh tr\u00f9ng b\u00f2 \u0111\u1ef1c \u0111\u00f4ng l\u1ea1nh trong \u1ed1ng ampoule c\u00f3 kh\u1ea3 n\u0103ng sinh s\u1ea3n th\u1ea5p h\u01a1n so v\u1edbi tinh tr\u00f9ng \u0111\u00f4ng l\u1ea1nh trong c\u1ecdng tr\u1eef m\u1eabu [Watson, 1979]. Cu\u1ed1i c\u00f9ng, c\u00f3 b\u1eb1ng ch\u1ee9ng gi\u00e1n ti\u1ebfp cho th\u1ea5y kh\u1ea3 n\u0103ng sinh s\u1ea3n c\u1ee7a tinh tr\u00f9ng ng\u01b0\u1eddi \u0111\u01b0\u1ee3c b\u1ea3o qu\u1ea3n l\u1ea1nh trong cryovial c\u00f3 th\u1ec3 th\u1ea5p h\u01a1n so v\u1edbi kh\u1ea3 n\u0103ng thu \u0111\u01b0\u1ee3c khi s\u1eed d\u1ee5ng c\u1ecdng tr\u1eef m\u1eabu [Mortimer, 2004a].<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Nguon_tham_khao\"><\/span>Ngu\u1ed3n tham kh\u1ea3o<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>McLaughlin E, Pacey A, Elliott T (eds) (1999) Safe Cryopreservation of Gametes and Embryos. World Wide Conferences on Reproductive Biology. Ladybrook Publishing, Perth, Australia, pp.105. Mortimer D (2004a) Current and future concepts and practices in human sperm cryobanking. RBM Online, 8,134-151. Watson PF (1979) The preservation of semen in mammals. In: Finn CA (ed) Oxford Reviews of Reproductive Biology. Oxford University Press, Oxford, UK, pp.283-350.<\/p>\n<p>Wood MJ (1999) The problems of storing gametes and embryos. Cryo-Letters, 20: 155-158.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u01afu v\u00e0 nh\u01b0\u1ee3c \u0111i\u1ec3m c\u1ee7a c\u00e1c v\u1eadt ch\u1ee9a m\u1eabu sinh h\u1ecdc kh\u00e1c nhau C\u1ecdng tr\u1eef m\u1eabu (truy\u1ec1n th\u1ed1ng) C\u1ecdng tr\u1eef m\u1eabu b\u1eb1ng nh\u1ef1a (\u0111\u00f4i khi c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 &#8220;c\u1ecdng tr\u1eef m\u1eabu Ph\u00e1p&#8221; ho\u1eb7c &#8220;paillettes&#8221;) \u0111\u01b0\u1ee3c Robert Cassou gi\u1edbi thi\u1ec7u l\u1ea7n \u0111\u1ea7u ti\u00ean v\u00e0o n\u0103m 1963 [Cassou, 1964]. \u00d4ng \u0111\u00e3 th\u00e0nh l\u1eadp c\u00f4ng ty Instruments<\/p>\n<div class=\"klb-readmore post-buttons\"><a class=\"button rounded primary\" href=\"https:\/\/biogroupvietnam.com\/vi\/blog\/uu-va-nhuoc-diem-cua-cac-vat-chua-mau-khac-nhau-la-gi\/\">Read More <i 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