{"id":3691,"date":"2025-08-18T19:52:20","date_gmt":"2025-08-18T12:52:20","guid":{"rendered":"http:\/\/biogroupvietnam-worldpress.local\/product\/import-placeholder-for-65\/"},"modified":"2025-12-17T14:51:17","modified_gmt":"2025-12-17T07:51:17","slug":"adam-cellt-plus-2","status":"publish","type":"product","link":"https:\/\/biogroupvietnam.com\/vi\/san-pham\/adam-cellt-plus-2\/","title":{"rendered":"M\u00e1y \u0110\u1ebfm T\u1ebf B\u00e0o T\u1ef1 \u0110\u1ed9ng ADAM-CellT (cGMP)"},"content":{"rendered":"<h2>ADAM-CellT l\u00e0 m\u00e1y \u0111\u1ebfm t\u1ebf b\u00e0o t\u1ef1 \u0111\u1ed9ng d\u00f9ng trong m\u00f4i tr\u01b0\u1eddng s\u1ea3n xu\u1ea5t cGMP. ADAM-CellT c\u00f3 m\u00e1y t\u00ednh b\u1ea3ng t\u00edch h\u1ee3p d\u1ec5 s\u1eed d\u1ee5ng v\u00e0 tu\u00e2n th\u1ee7 21 CFR ph\u1ea7n 11. Khi ch\u1ebf \u0111\u1ed9 21 CFR ph\u1ea7n 11 \u0111\u01b0\u1ee3c k\u00edch ho\u1ea1t, b\u1ea5t k\u1ef3 ng\u01b0\u1eddi d\u00f9ng n\u00e0o c\u0169ng kh\u00f4ng th\u1ec3 s\u1eeda \u0111\u1ed5i d\u1eef li\u1ec7u.<\/h2>\n<h3><strong>C\u00e1c t\u00ednh n\u0103ng v\u00e0 ti\u1ec7n \u00edch ch\u00ednh c\u1ee7a m\u00e1y ADAM-CellT:<\/strong><\/h3>\n<ul>\n<li>Cho k\u1ebft qu\u1ea3 \u0111o d\u01b0\u1edbi 25 gi\u00e2y.<\/li>\n<li>Ki\u1ec3m tra ch\u1ea5t l\u01b0\u1ee3ng li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o.<\/li>\n<li>Tu\u00e2n th\u1ee7 21 CFR ph\u1ea7n 11.<\/li>\n<li>\u1ee8ng d\u1ee5ng \u0111\u1ebfm c\u00e1c lo\u1ea1i t\u1ebf b\u00e0o nh\u01b0: t\u1ebf b\u00e0o g\u1ed1c, t\u1ebf b\u00e0o CAR-T, t\u1ebf b\u00e0o CAR-NK, t\u1ebf b\u00e0o g\u1ed1c trung m\u00f4 t\u1eeb m\u00f4 m\u1ee1.<\/li>\n<li>\u0110\u1ebfm t\u1ebf b\u00e0o ch\u00ednh x\u00e1c v\u00e0 \u0111\u1ebfm t\u1ebf b\u00e0o s\u1ed1ng.<\/li>\n<li>Ph\u00e2n t\u00edch h\u00ecnh \u1ea3nh t\u1ef1 \u0111\u1ed9ng.<\/li>\n<li>B\u1ed9 nh\u1edb b\u1ed5 sung 4TB \u0111\u1ec3 sao l\u01b0u v\u00e0 ph\u1ee5c h\u1ed3i d\u1eef li\u1ec7u.<\/li>\n<\/ul>\n<h3><strong>\u0110\u1ebfm t\u1ebf b\u00e0o t\u1ed5ng s\u1ed1 v\u00e0 t\u1ebf b\u00e0o s\u1ed1ng b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p nhu\u1ed9m propidium iodide (PI) b\u1eb1ng m\u00e1y ADAM-CellT<\/strong><\/h3>\n<p>Sau khi c\u00e1c m\u1eabu \u0111\u01b0\u1ee3c nhu\u1ed9m b\u1eb1ng thu\u1ed1c nhu\u1ed9m hu\u1ef3nh quang, propidium iodide, ch\u1ea5t xen k\u1ebd DNA \u0111\u1ec3 nhu\u1ed9m nh\u00e2n t\u1ebf b\u00e0o \u0111\u00edch, ADAM-CellT s\u1ebd t\u1ef1 \u0111\u1ed9ng ch\u1ee5p \u1ea3nh hu\u1ef3nh quang. H\u00ecnh \u1ea3nh thu \u0111\u01b0\u1ee3c \u0111\u01b0\u1ee3c x\u1eed l\u00fd b\u1eb1ng ph\u1ea7n m\u1ec1m ph\u00e2n t\u00edch h\u00ecnh \u1ea3nh t\u00edch h\u1ee3p b\u00ean trong h\u1ec7 th\u1ed1ng.<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" src=\"https:\/\/biogroupvietnam.com\/uploads\/F8CZdl6ww0bOI5AQEJHR9DjyuRGpraXFzqBaJi3q.png\" alt=\"\" width=\"729\" height=\"228\" \/><\/p>\n<h3><strong>Qu\u1ea3n l\u00fd d\u1eef\u00a0li\u1ec7u &#8211; tu\u00e2n th\u1ee7 21 CFR ph\u1ea7n 11<\/strong><\/h3>\n<p>ADAM-CellT tu\u00e2n th\u1ee7 21 CFR ph\u1ea7n 11 l\u00e0 quy \u0111\u1ecbnh v\u1ec1 h\u1ed3 s\u01a1 \u0111i\u1ec7n t\u1eed v\u00e0 ch\u1eef k\u00fd \u0111\u1ec3 s\u1eed d\u1ee5ng trong c\u00e1c c\u01a1 s\u1edf cGMP. Khi k\u00edch ho\u1ea1t ch\u1ebf \u0111\u1ed9 21 CFR Part 11, b\u1ea5t k\u1ef3 ng\u01b0\u1eddi d\u00f9ng n\u00e0o c\u0169ng kh\u00f4ng th\u1ec3 s\u1eeda \u0111\u1ed5i d\u1eef li\u1ec7u. M\u1ecdi h\u00e0nh \u0111\u1ed9ng c\u1ee7a ng\u01b0\u1eddi d\u00f9ng \u0111\u1ec1u \u0111\u01b0\u1ee3c ghi l\u1ea1i trong qu\u00e1 tr\u00ecnh ki\u1ec3m tra bao g\u1ed3m ng\u00e0y, gi\u1edd v\u00e0 c\u00e1c chi ti\u1ebft c\u1ee5 th\u1ec3 c\u1ee7a h\u00e0nh \u0111\u1ed9ng. Ch\u1eef k\u00fd \u0111i\u1ec7n t\u1eed d\u1ef1a tr\u00ean sinh tr\u1eafc h\u1ecdc \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o r\u1eb1ng ch\u00fang kh\u00f4ng th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng l\u1ea1i b\u1edfi ho\u1eb7c ch\u1ec9 \u0111\u1ecbnh cho b\u1ea5t k\u1ef3 ai kh\u00e1c.<\/p>\n<h3><strong>Qu\u1ea3n l\u00fd ng\u01b0\u1eddi d\u00f9ng &#8211; C\u1ea5p \u0111\u1ed9 truy c\u1eadp v\u00e0 quy\u1ec1n c\u1ee7a ng\u01b0\u1eddi d\u00f9ng<\/strong><\/h3>\n<p>21 CFR Ph\u1ea7n 11 bao g\u1ed3m gi\u1edbi h\u1ea1n quy\u1ec1n truy c\u1eadp h\u1ec7 th\u1ed1ng \u0111\u1ed1i v\u1edbi c\u00e1c c\u00e1 nh\u00e2n \u0111\u01b0\u1ee3c \u1ee7y quy\u1ec1n. Ng\u01b0\u1eddi d\u00f9ng c\u00f3 th\u1ec3 ki\u1ec3m so\u00e1t quy\u1ec1n truy c\u1eadp trong ph\u1ea7n m\u1ec1m. N\u00f3 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 t\u00e1ch bi\u1ec7t 3 nh\u00f3m kh\u00e1c nhau &#8211; Qu\u1ea3n tr\u1ecb vi\u00ean, Ng\u01b0\u1eddi gi\u00e1m s\u00e1t v\u00e0 Ng\u01b0\u1eddi d\u00f9ng.<\/p>\n<h3><strong>\u1ee8ng d\u1ee5ng \u1edf t\u1ea5t c\u1ea3 c\u00e1c b\u01b0\u1edbc trong s\u1ea3n xu\u1ea5t s\u1ea3n xu\u1ea5t t\u1ebf b\u00e0o CAR-T<\/strong><\/h3>\n<p>D\u1ec5 d\u00e0ng theo d\u00f5i t\u1ea5t c\u1ea3 c\u00e1c b\u01b0\u1edbc kh\u00e1c nhau c\u1ee7a qu\u00e1 tr\u00ecnh tinh s\u1ea1ch, t\u0103ng sinh v\u00e0 t\u1ea1o c\u00f4ng th\u1ee9c (formulation) t\u1ebf b\u00e0o CAR-T b\u1eb1ng m\u00e1y ADAM-CellT \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o k\u1ebft qu\u1ea3 \u0111\u1ebfm ch\u00ednh x\u00e1c v\u00e0 \u0111\u00e1ng tin c\u1eady. M\u00e1y ADAM-CellT c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong m\u00f4i tr\u01b0\u1eddng s\u1ea3n xu\u1ea5t cGMP, ki\u1ec3m so\u00e1t qu\u00e1 tr\u00ecnh v\u00e0 ki\u1ec3m so\u00e1t ch\u1ea5t l\u01b0\u1ee3ng c\u1ee7a t\u1ebf b\u00e0o CAR-T.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biogroupvietnam.com\/uploads\/zVFzme7YbiAItGFWM5rGccgXWaZov0wYw6IX9BtR.png\" alt=\"\" width=\"973\" height=\"199\" \/><\/p>\n<h3><strong>Ph\u00e2n t\u00edch d\u1eef li\u1ec7u &#8211; Ki\u1ec3m tra hi\u1ec7u su\u1ea5t t\u1eeb c\u00e1c t\u1ebf b\u00e0o T \u0111\u01b0\u1ee3c ph\u00e2n l\u1eadp<\/strong><\/h3>\n<p><img decoding=\"async\" src=\"https:\/\/biogroupvietnam.com\/uploads\/BoC2KoYyfn0sMqNgVYBjwRPZeIQeS9xuiMgrJ581.png\" alt=\"\" width=\"974\" height=\"296\" \/><\/p>\n<p>H\u00ecnh 1: H\u1ed3 s\u01a1 c\u1ee7a c\u00e1c t\u1ebf b\u00e0o T \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 hi\u1ec7u su\u1ea5t &#8211; Ph\u00e2n t\u00edch t\u1ebf b\u00e0o d\u00f2ng bi\u1ec3u hi\u1ec7n CD3 tr\u00ean t\u1ebf b\u00e0o lympho m\u00e1u ngo\u1ea1i vi c\u1ee7a ng\u01b0\u1eddi kh\u00f4ng \u0111\u01b0\u1ee3c s\u1eafp x\u1ebfp (unsorted) (WBC; b\u1ea3ng b\u00ean tr\u00e1i) ho\u1eb7c \u0111\u00e3 \u0111\u01b0\u1ee3c s\u1eafp x\u1ebfp (sorted) (t\u1ebf b\u00e0o T c\u00f4 l\u1eadp; b\u1ea3ng b\u00ean ph\u1ea3i).<\/p>\n<h3><strong>Ph\u00e2n t\u00edch d\u1eef li\u1ec7u &#8211; Ki\u1ec3m tra hi\u1ec7u su\u1ea5t t\u1eeb c\u00e1c t\u1ebf b\u00e0o T \u0111\u01b0\u1ee3c k\u00edch ho\u1ea1t<\/strong><\/h3>\n<h3><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/biogroupvietnam.com\/uploads\/hu5nE563dPPJnO3d5JNUyokGAFbQa0kGdvW9arY4.png\" alt=\"\" width=\"974\" height=\"296\" \/><\/h3>\n<p>C\u00e1c ki\u1ec3u h\u00ecnh c\u1ee7a t\u1ebf b\u00e0o T ho\u1ea1t h\u00f3a \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 hi\u1ec7u su\u1ea5t &#8211; Ph\u00e2n t\u00edch t\u1ebf b\u00e0o d\u00f2ng bi\u1ec3u hi\u1ec7n CD25 tr\u00ean t\u1ebf b\u00e0o T \u0111\u01b0\u1ee3c k\u00edch ho\u1ea1t.<\/p>\n<h3><strong>\u0110\u1ed9 ch\u00ednh x\u00e1c c\u1ee7a h\u1ec7 th\u1ed1ng \u2013 Th\u1ea9m \u0111\u1ecbnh (validation) m\u00e1y ADAM-CellT<\/strong><\/h3>\n<p>H\u1ea1t hi\u1ec7u chu\u1ea9n ADAM (ADAM calibration beads) cho ph\u00e9p ch\u1ea9n \u0111o\u00e1n nhanh ch\u00f3ng khi c\u00f3 s\u1ef1 c\u1ed1, \u0111\u1ea3m b\u1ea3o \u0111\u1ed9 ch\u00ednh x\u00e1c c\u1ee7a thi\u1ebft b\u1ecb. Th\u1ea9m \u0111\u1ecbnh l\u1eafp \u0111\u1eb7t (IQ), Th\u1ea9m \u0111\u1ecbnh v\u1eadn h\u00e0nh (OQ) v\u00e0 Th\u1ea9m \u0111\u1ecbnh hi\u1ec7u n\u0103ng (PQ) \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf \u0111\u1ec3 x\u00e1c nh\u1eadn hi\u1ec7u su\u1ea5t c\u1ee7a thi\u1ebft b\u1ecb.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>ADAM-CellT l\u00e0 m\u00e1y \u0111\u1ebfm t\u1ebf b\u00e0o t\u1ef1 \u0111\u1ed9ng d\u00f9ng trong m\u00f4i tr\u01b0\u1eddng s\u1ea3n xu\u1ea5t cGMP. ADAM-CellT c\u00f3 m\u00e1y t\u00ednh b\u1ea3ng t\u00edch h\u1ee3p d\u1ec5 s\u1eed d\u1ee5ng v\u00e0 tu\u00e2n th\u1ee7 21 CFR ph\u1ea7n 11. Khi ch\u1ebf \u0111\u1ed9 21 CFR ph\u1ea7n 11 \u0111\u01b0\u1ee3c k\u00edch ho\u1ea1t, b\u1ea5t k\u1ef3 ng\u01b0\u1eddi d\u00f9ng n\u00e0o c\u0169ng kh\u00f4ng th\u1ec3 s\u1eeda \u0111\u1ed5i d\u1eef li\u1ec7u. C\u00e1c<\/p>\n<div class=\"klb-readmore post-buttons\"><a class=\"button rounded primary\" href=\"https:\/\/biogroupvietnam.com\/vi\/san-pham\/adam-cellt-plus-2\/\">Read More <i class=\"klbth-icon-right-arrow\"><\/i><\/a><\/div>\n","protected":false},"featured_media":8974,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[134],"product_cat":[176],"product_tag":[],"class_list":{"0":"post-3691","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_brand-nanoentek","7":"product_cat-dem-te-bao-chuan-gmp","9":"first","10":"outofstock","11":"shipping-taxable","12":"product-type-simple"},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>M\u00e1y \u0110\u1ebfm T\u1ebf B\u00e0o T\u1ef1 \u0110\u1ed9ng ADAM-CellT (cGMP)<\/title>\n<meta name=\"description\" content=\"ADAM-CellT l\u00e0 m\u00e1y 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