{"id":4033,"date":"2025-08-18T19:55:44","date_gmt":"2025-08-18T12:55:44","guid":{"rendered":"http:\/\/biogroupvietnam-worldpress.local\/product\/import-placeholder-for-241\/"},"modified":"2026-04-02T10:38:09","modified_gmt":"2026-04-02T03:38:09","slug":"bo-kit-hepaticult-organoid-kit-human","status":"publish","type":"product","link":"https:\/\/biogroupvietnam.com\/vi\/san-pham\/bo-kit-hepaticult-organoid-kit-human\/","title":{"rendered":"B\u1ed9 kit HepatiCult\u2122 Organoid Kit (Human)"},"content":{"rendered":"<h3 style=\"text-align: justify;\"><strong>T\u1ed5ng quan v\u1ec1 B\u1ed9 kit HepatiCult\u2122 Organoid Kit (Human)<\/strong><\/h3>\n<p>B\u1ed9 kit HepatiCult\u2122 Organoid Kit (Human) t\u1ea1o ra, m\u1edf r\u1ed9ng v\u00e0 bi\u1ec7t h\u00f3a c\u00e1c c\u01a1 quan gan ng\u01b0\u1eddi c\u00f3 li\u00ean quan \u0111\u1ebfn sinh l\u00fd m\u1ed9t c\u00e1ch \u0111\u00e1ng tin c\u1eady. So v\u1edbi c\u00e1c h\u1ec7 th\u1ed1ng m\u00f4 h\u00ecnh \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng theo truy\u1ec1n th\u1ed1ng nh\u01b0 d\u00f2ng t\u1ebf b\u00e0o v\u00e0 m\u00f4 h\u00ecnh \u0111\u1ed9ng v\u1eadt, c\u00e1c c\u01a1 quan gan ng\u01b0\u1eddi cung c\u1ea5p m\u1ed9t h\u1ec7 th\u1ed1ng m\u00f4 h\u00ecnh c\u00f3 li\u00ean quan h\u01a1n \u0111\u1ec3 nghi\u00ean c\u1ee9u s\u1ef1 ph\u00e1t tri\u1ec3n, t\u00e1i t\u1ea1o, chuy\u1ec3n h\u00f3a v\u00e0 b\u1ec7nh t\u1eadt c\u1ee7a gan.<\/p>\n<p>B\u1ed9 kit ch\u1ee9a t\u1ea5t c\u1ea3 c\u00e1c th\u00e0nh ph\u1ea7n c\u1ea7n thi\u1ebft \u0111\u1ec3 nu\u00f4i c\u1ea5y organoid gan ng\u01b0\u1eddi t\u1eeb m\u00f4 gan ng\u01b0\u1eddi t\u01b0\u01a1i ho\u1eb7c \u0111\u00f4ng l\u1ea1nh.<\/p>\n<h3><strong>T\u00ednh n\u0103ng n\u1ed5i b\u1eadt<\/strong><\/h3>\n<ul>\n<li>Cung c\u1ea5p m\u1ed9t h\u1ec7 th\u1ed1ng nu\u00f4i c\u1ea5y ho\u00e0n ch\u1ec9nh \u0111\u1ec3 thi\u1ebft l\u1eadp, duy tr\u00ec v\u00e0 bi\u1ec7t h\u00f3a c\u00e1c organoid gan ng\u01b0\u1eddi<\/li>\n<li>\n<p style=\"text-align: justify;\">Cho ph\u00e9p kh\u1edfi \u0111\u1ea7u organoid hi\u1ec7u qu\u1ea3 tr\u00ean c\u00e1c m\u00f4 gan c\u1ee7a ng\u01b0\u1eddi hi\u1ebfn t\u1eb7ng kh\u00e1c nhau<\/p>\n<\/li>\n<li>\n<p style=\"text-align: justify;\">T\u1ea1o ra c\u00e1c organoid gan tr\u01b0\u1edfng th\u00e0nh th\u1ec3 hi\u1ec7n ho\u1ea1t \u0111\u1ed9ng c\u1ee7a CYP3A4<\/p>\n<\/li>\n<li>\n<p style=\"text-align: justify;\">Cho ph\u00e9p linh ho\u1ea1t th\u1eed nghi\u1ec7m v\u1edbi c\u00e1c \u0111\u1ecbnh d\u1ea1ng nu\u00f4i c\u1ea5y kh\u00e1c nhau<\/p>\n<\/li>\n<\/ul>\n<h3><strong>\u1ee8ng d\u1ee5ng<\/strong><\/h3>\n<p>Nu\u00f4i c\u1ea5y organoid<\/p>\n<h3><strong>Th\u00e0nh ph\u1ea7n HepatiCult\u2122 Organoid Kit (Human) (Catalog #100-0386)<\/strong><\/h3>\n<ul>\n<li><strong>HepatiCult\u2122 Organoid Basal Medium (Human) <\/strong>(Catalog #100-0387), 3 chai x 95 mL\/chai: T\u1ea1o ra organoid gan m\u1ed9t c\u00e1ch hi\u1ec7u qu\u1ea3 tr\u00ean nhi\u1ec1u d\u00f2ng hi\u1ebfn t\u1eb7ng kh\u00e1c nhau.<\/li>\n<li><strong>Organoid Supplement <\/strong>(Catalog #100-0191), chai 50 mL:B\u1ed5 tr\u1ee3 cho qu\u00e1 tr\u00ecnh\u00a0t\u1ea1o ra organoid gan m\u1ed9t c\u00e1ch hi\u1ec7u qu\u1ea3<\/li>\n<li><strong>HepatiCult\u2122 Organoid Growth Supplement (Human) <\/strong>(catalog #100-0389), 2 l\u1ecd x 5 mL\/l\u1ecd: M\u1edf r\u1ed9ng v\u00e0 duy tr\u00ec organoid gan cho m\u1ee5c \u0111\u00edch th\u1eed nghi\u1ec7m ho\u1eb7c l\u01b0u tr\u1eef sinh h\u1ecdc trong t\u01b0\u01a1ng lai.<\/li>\n<li><strong>HepatiCult\u2122 Organoid Differentiation Supplement (Human)<\/strong> (catalog #100-0388), 5 mL\/l\u1ecd: T\u1ea1o ra organoid tr\u01b0\u1edfng th\u00e0nh th\u1ec3 hi\u1ec7n ch\u1ee9c n\u0103ng gan, bao g\u1ed3m ho\u1ea1t \u0111\u1ed9ng c\u1ee7a CYP3A4. C\u00e1c organoid n\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh cho ph\u00f9 h\u1ee3p v\u1edbi nhi\u1ec1u quy tr\u00ecnh nu\u00f4i c\u1ea5y, bao g\u1ed3m nu\u00f4i c\u1ea5y l\u1edbp \u0111\u01a1n 2D, nu\u00f4i c\u1ea5y huy\u1ec1n ph\u00f9 v\u00e0 x\u00e9t nghi\u1ec7m th\u00f4ng l\u01b0\u1ee3ng cao<\/li>\n<\/ul>\n<h3><strong>K\u1ebft qu\u1ea3 d\u1ef1 ki\u1ebfn<\/strong><\/h3>\n<figure class=\"image\"><img fetchpriority=\"high\" decoding=\"async\" style=\"aspect-ratio: 586\/448;\" src=\"https:\/\/biogroupvietnam.com\/uploads\/YX8Qfw5v1fC04kRclIwbK1Z16PjaS106lZ8JYX3E.png\" width=\"586\" height=\"448\" \/><\/figure>\n<p style=\"text-align: center;\"><em>H\u00ecnh 1. B\u1ed9 kit HepatiCult\u2122 Organoid (Ng\u01b0\u1eddi) cho ph\u00e9p kh\u1edfi \u0111\u1ea7u, m\u1edf r\u1ed9ng v\u00e0 bi\u1ec7t h\u00f3a organoid gan<\/em><\/p>\n<p style=\"text-align: justify;\">C\u00e1c organoid gan c\u1ee7a ng\u01b0\u1eddi c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c nu\u00f4i c\u1ea5y t\u1eeb c\u00e1c \u1ed1ng gan c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb m\u00f4 gan ng\u01b0\u1eddi b\u00ecnh th\u01b0\u1eddng b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng B\u1ed9 kit HepatiCult\u2122 Organoid (Ng\u01b0\u1eddi). (A) Nu\u00f4i c\u1ea5y trong M\u00f4i tr\u01b0\u1eddng HepatiCult\u2122 Organoid Initiation Medium\u00a0(OIM; Ng\u01b0\u1eddi) ho\u1eb7c M\u00f4i tr\u01b0\u1eddng HepatiCult\u2122 Organoid Growth (OGM; Ng\u01b0\u1eddi) (xem B\u1ea3ng 1 b\u00ean d\u01b0\u1edbi) v\u00e0 sau \u0111\u00f3 chuy\u1ec3n qua HepatiCult\u2122 OGM \u0111\u1ec3 m\u1edf r\u1ed9ng. (B) Sau khi chuy\u1ec3n qua HepatiCult\u2122 OGM 2-3 l\u1ea7n, m\u1eabu c\u1ea5y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c chuy\u1ec3n sang M\u00f4i tr\u01b0\u1eddng bi\u1ec7t h\u00f3a HepatiCult\u2122 Organoid (ODM; Ng\u01b0\u1eddi) \u0111\u1ec3 bi\u1ec7t h\u00f3a c\u00e1c organoid gan th\u00e0nh c\u00e1c lo\u1ea1i t\u1ebf b\u00e0o gan tr\u01b0\u1edfng th\u00e0nh. Tham kh\u1ea3o H\u01b0\u1edbng d\u1eabn s\u1ea3n ph\u1ea9m (T\u00e0i li\u1ec7u #10000008301) \u0111\u1ec3 bi\u1ebft quy tr\u00ecnh nu\u00f4i c\u1ea5y \u0111\u1ea7y \u0111\u1ee7.<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><em>B\u1ea3ng 1. Khuy\u1ebfn ngh\u1ecb v\u1ec1 s\u1ea3n ph\u1ea9m \u0111\u1ec3 kh\u1edfi \u0111\u1ea7u, m\u1edf r\u1ed9ng v\u00e0 bi\u1ec7t h\u00f3a organoid gan<\/em><\/p>\n<figure class=\"image\"><img decoding=\"async\" style=\"aspect-ratio: 844\/308;\" src=\"https:\/\/biogroupvietnam.com\/uploads\/0t9YAsr0lpNGDQ161nd8w9VVL5EClf2BucuommnG.png\" width=\"844\" height=\"308\" \/><\/figure>\n<p style=\"text-align: justify;\">C\u1ea5u h\u00ecnh \u0111\u01b0\u1ee3c \u0111\u1ec1 xu\u1ea5t c\u1ee7a B\u1ed9 kit HepatiCult\u2122 Organoid (Ng\u01b0\u1eddi) c\u00f3 th\u1ec3 kh\u00e1c nhau d\u1ef1a v\u00e0o nguy\u00ean li\u1ec7u ban \u0111\u1ea7u v\u00e0 m\u1ee5c ti\u00eau th\u1eed nghi\u1ec7m. Khi thi\u1ebft l\u1eadp m\u1eabu nu\u00f4i c\u1ea5y organoid gan t\u1eeb m\u00f4 gan ng\u01b0\u1eddi, n\u00ean s\u1eed d\u1ee5ng HepatiCult\u2122 Organoid Initiation Medium (OIM; Ng\u01b0\u1eddi) \u0111\u1ec3 kh\u1edfi \u0111\u1ea7u nu\u00f4i c\u1ea5y organoid hi\u1ec7u qu\u1ea3 (xem H\u00ecnh 2 b\u00ean d\u01b0\u1edbi). M\u00f4i tr\u01b0\u1eddng HepatiCult\u2122 Organoid Growth Medium (OGM; Ng\u01b0\u1eddi) h\u1ed7 tr\u1ee3 vi\u1ec7c m\u1edf r\u1ed9ng c\u00e1c organoid \u0111\u00e3 thi\u1ebft l\u1eadp (t\u01b0\u01a1i trong nu\u00f4i c\u1ea5y ho\u1eb7c b\u1ea3o qu\u1ea3n \u0111\u00f4ng l\u1ea1nh). C\u00e1c organoid n\u00e0y n\u00ean \u0111\u01b0\u1ee3c duy tr\u00ec trong 2-3 l\u1ea7n c\u1ea5y tr\u01b0\u1edbc khi bi\u1ec7t h\u00f3a th\u00eam b\u1eb1ng M\u00f4i tr\u01b0\u1eddng bi\u1ec7t h\u00f3a HepatiCult\u2122 Organoid Differentiation Medium (ODM). Tham kh\u1ea3o\u00a0H\u01b0\u1edbng d\u1eabn s\u1ea3n ph\u1ea9m (T\u00e0i li\u1ec7u #10000008301) \u0111\u1ec3 bi\u1ebft \u0111\u1ea7y \u0111\u1ee7 c\u00e1c quy tr\u00ecnh nu\u00f4i c\u1ea5y.<\/p>\n<figure class=\"image\"><img decoding=\"async\" style=\"aspect-ratio: 755\/341;\" src=\"https:\/\/biogroupvietnam.com\/uploads\/FEIBvKWvXE8NM0Rn39sqkgwym6BeF5O3z6OEqsaP.png\" width=\"755\" height=\"341\" \/><\/figure>\n<p style=\"text-align: center;\"><em>H\u00ecnh 2. B\u1ed9 d\u1ee5ng c\u1ee5 HepatiCult\u2122 Organoid (Ng\u01b0\u1eddi) cung c\u1ea5p kh\u1edfi \u0111\u1ea7u Organoid hi\u1ec7u qu\u1ea3 t\u1eeb m\u00f4 gan ng\u01b0\u1eddi<\/em><\/p>\n<p style=\"text-align: justify;\">(A) Nu\u00f4i c\u1ea5y organoid \u0111\u01b0\u1ee3c kh\u1edfi \u0111\u1ea7u trong HepatiCult\u2122 OIM, sau \u0111\u00f3 (B) chuy\u1ec3n v\u00e0o HepatiCult\u2122 OGM. \u0110\u1ed1i v\u1edbi \u0111i\u1ec1u ki\u1ec7n nu\u00f4i c\u1ea5y kh\u00f4ng c\u00f3 huy\u1ebft thanh, nu\u00f4i c\u1ea5y organoid \u0111\u01b0\u1ee3c (C) kh\u1edfi \u0111\u1ea7u v\u00e0 (D) chuy\u1ec3n v\u00e0o HepatiCult\u2122 OGM. H\u00ecnh \u1ea3nh nu\u00f4i c\u1ea5y \u0111\u01b0\u1ee3c hi\u1ec3n th\u1ecb t\u1eeb (A, C) ng\u00e0y 15 sau khi kh\u1edfi \u0111\u1ea7u v\u00e0 (B, D) v\u00e0o ng\u00e0y 8 c\u1ee7a l\u1ea7n c\u1ea5y chuy\u1ec1n \u0111\u1ea7u ti\u00ean. (E) \u0110\u1ecbnh l\u01b0\u1ee3ng hi\u1ec7u qu\u1ea3 kh\u1edfi \u0111\u1ea7u organoid cho th\u1ea5y s\u1ea3n l\u01b0\u1ee3ng organoid cao h\u01a1n \u0111\u00e1ng k\u1ec3 trong HepatiCult\u2122 OIM tr\u00ean m\u1ed7i gam m\u00f4 gan ng\u01b0\u1eddi (mean \u00b1 SD; n = 14).<\/p>\n<figure class=\"image\"><img loading=\"lazy\" decoding=\"async\" style=\"aspect-ratio: 844\/305;\" src=\"https:\/\/biogroupvietnam.com\/uploads\/W0CfgdZ4fV73ih0z1r2TlxZ03mrrw5Sqoh4wCnC0.png\" width=\"844\" height=\"305\" \/><\/figure>\n<p><em>H\u00ecnh 3: M\u00f4i tr\u01b0\u1eddng HepatiCult\u2122 Organoid Initiation (Ng\u01b0\u1eddi) h\u1ed7 tr\u1ee3 vi\u1ec7c thi\u1ebft l\u1eadp organoid m\u1ea1nh m\u1ebd tr\u00ean nhi\u1ec1u m\u1eabu m\u00f4 gan hi\u1ebfn t\u1eb7ng<\/em><\/p>\n<p style=\"text-align: justify;\">Organoid kh\u1edfi \u0111\u1ea7u t\u1eeb 4 m\u1eabu m\u00f4 hi\u1ebfn t\u1eb7ng (A-D) bi\u1ec3u hi\u1ec7n t\u00ednh kh\u00f4ng \u0111\u1ed3ng nh\u1ea5t v\u1ec1 m\u1eb7t h\u00ecnh th\u00e1i sau 15 ng\u00e0y kh\u1edfi \u0111\u1ea7u. T\u1ea5t c\u1ea3 c\u00e1c m\u1eabu nu\u00f4i c\u1ea5y kh\u1edfi \u0111\u1ea7u sau \u0111\u00f3 \u0111\u01b0\u1ee3c m\u1edf r\u1ed9ng trong HepatiCult\u2122 OGM b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng t\u1ef7 l\u1ec7 truy\u1ec1n 1:1 (E-H), t\u1ea1o ra c\u00e1c organoid kh\u1ecfe m\u1ea1nh v\u00e0o cu\u1ed1i giai \u0111o\u1ea1n \u0111\u1ea7u ti\u00ean.<\/p>\n<figure class=\"image\"><img loading=\"lazy\" decoding=\"async\" style=\"aspect-ratio: 646\/366;\" src=\"https:\/\/biogroupvietnam.com\/uploads\/9kJRUttkRMOyrr14yk20cWSrZpl24MEWi7xa2x8V.png\" width=\"646\" height=\"366\" \/><\/figure>\n<p><em>H\u00ecnh 4. S\u1ef1 m\u1edf r\u1ed9ng c\u1ee7a c\u00e1c m\u1eabu nu\u00f4i c\u1ea5y organoid trong HepatiCult\u2122 Organoid Growth Medium<\/em><\/p>\n<p>C\u00e1c organoid gan cho th\u1ea5y s\u1ef1 ph\u00e1t tri\u1ec3n hi\u1ec7u qu\u1ea3 trong HepatiCult\u2122 OGM tr\u00ean nhi\u1ec1u ng\u01b0\u1eddi hi\u1ebfn t\u1eb7ng v\u00e0 c\u00e1c l\u1ea7n chuy\u1ec1n v\u1edbi ti\u1ec1m n\u0103ng nu\u00f4i c\u1ea5y v\u00f4 th\u1eddi h\u1ea1n. C\u00e1c organoid \u0111\u01b0\u1ee3c kh\u1edfi \u0111\u1ea7u b\u1eb1ng quy tr\u00ecnh kh\u00f4ng c\u00f3 huy\u1ebft thanh cho th\u1ea5y t\u1ed1c \u0111\u1ed9 t\u0103ng tr\u01b0\u1edfng t\u01b0\u01a1ng \u0111\u01b0\u01a1ng khi \u0111\u01b0\u1ee3c m\u1edf r\u1ed9ng trong HepatiCult\u2122 OGM (c\u00e1c d\u1ea5u hi\u1ec7u (marker) m\u1edf).<\/p>\n<figure class=\"image\"><img loading=\"lazy\" decoding=\"async\" style=\"aspect-ratio: 700\/185;\" src=\"https:\/\/biogroupvietnam.com\/uploads\/SQl9VGYRsSOhzJX7HNHvQKOBMZosNWbtwQYo4Ssi.png\" width=\"700\" height=\"185\" \/><\/figure>\n<p><em>H\u00ecnh 5. C\u00e1c c\u01a1 quan gan t\u0103ng sinh th\u1ec3 hi\u1ec7n c\u00e1c \u0111\u1eb7c \u0111i\u1ec3m c\u1ee7a ti\u1ec1n th\u00e2n gan<\/em><\/p>\n<p>C\u00e1c c\u01a1 quan gan ng\u01b0\u1eddi \u0111\u01b0\u1ee3c nu\u00f4i c\u1ea5y trong HepatiCult\u2122 OGM th\u1ec3 hi\u1ec7n c\u00e1c \u0111\u1eb7c \u0111i\u1ec3m c\u1ee7a ti\u1ec1n th\u00e2n gan t\u0103ng sinh \u0111\u01b0\u1ee3c quan s\u00e1t th\u1ea5y th\u00f4ng qua nhu\u1ed9m h\u00f3a m\u00f4 mi\u1ec5n d\u1ecbch t\u1ebf b\u00e0o c\u1ee7a (A) KI67, (B) HNF4A v\u00e0 (C) SOX9. C\u00e1c c\u01a1 quan gan t\u0103ng sinh c\u0169ng th\u1ec3 hi\u1ec7n c\u00e1c \u0111\u1eb7c \u0111i\u1ec3m c\u1ee7a bi\u1ec3u m\u00f4 gan bao g\u1ed3m bi\u1ec3u hi\u1ec7n c\u1ee7a (A) EPCAM. (B, C) Nh\u00e2n \u0111\u01b0\u1ee3c nhu\u1ed9m t\u01b0\u01a1ng ph\u1ea3n v\u1edbi DAPI.<\/p>\n<p><a href=\"https:\/\/www.stemcell.com\/hepaticult-organoid-kit-human.html\">Xem th\u00eam d\u1eef li\u1ec7u s\u1ea3n ph\u1ea9m t\u1ea1i \u0111\u00e2y.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>T\u1ed5ng quan v\u1ec1 B\u1ed9 kit HepatiCult\u2122 Organoid Kit (Human) B\u1ed9 kit HepatiCult\u2122 Organoid Kit (Human) t\u1ea1o ra, m\u1edf r\u1ed9ng v\u00e0 bi\u1ec7t h\u00f3a c\u00e1c c\u01a1 quan gan ng\u01b0\u1eddi c\u00f3 li\u00ean quan \u0111\u1ebfn sinh l\u00fd m\u1ed9t c\u00e1ch \u0111\u00e1ng tin c\u1eady. So v\u1edbi c\u00e1c h\u1ec7 th\u1ed1ng m\u00f4 h\u00ecnh \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng theo truy\u1ec1n th\u1ed1ng nh\u01b0 d\u00f2ng t\u1ebf b\u00e0o<\/p>\n<div class=\"klb-readmore post-buttons\"><a class=\"button rounded primary\" href=\"https:\/\/biogroupvietnam.com\/vi\/san-pham\/bo-kit-hepaticult-organoid-kit-human\/\">Read More <i class=\"klbth-icon-right-arrow\"><\/i><\/a><\/div>\n","protected":false},"featured_media":10131,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[127],"product_cat":[88],"product_tag":[],"class_list":{"0":"post-4033","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_brand-stemcell-technologies","7":"product_cat-organoids","9":"first","10":"outofstock","11":"shipping-taxable","12":"product-type-simple"},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ 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