{"id":4403,"date":"2024-02-25T08:57:26","date_gmt":"2024-02-25T08:57:26","guid":{"rendered":"http:\/\/biogroupvietnam-worldpress.local\/service\/what-is-toc-system-compatibility-assessment-sst-why-when-should-sst-be-performed\/"},"modified":"2025-09-29T13:07:35","modified_gmt":"2025-09-29T06:07:35","slug":"danh-gia-do-tuong-thich-he-thong-toc-sst-la-gi-tai-sao-khi-nao-can-thuc-hien-sst","status":"publish","type":"service","link":"https:\/\/biogroupvietnam.com\/vi\/dich-vu\/danh-gia-do-tuong-thich-he-thong-toc-sst-la-gi-tai-sao-khi-nao-can-thuc-hien-sst\/","title":{"rendered":"\u0110\u00e1nh Gi\u00e1 \u0110\u1ed9 T\u01b0\u01a1ng Th\u00edch H\u1ec7 Th\u1ed1ng TOC (SST) L\u00e0 G\u00ec? T\u1ea1i Sao & Khi N\u00e0o C\u1ea7n Th\u1ef1c Hi\u1ec7n SST?"},"content":{"rendered":"

\u0110\u00e1nh gi\u00e1 \u0111\u1ed9 t\u01b0\u01a1ng th\u00edch h\u1ec7 th\u1ed1ng TOC (SST) l\u00e0 g\u00ec? T\u1ea1i sao c\u1ea7n th\u1ef1c hi\u1ec7n SST?<\/strong><\/p>\n

\u0110\u1ed9 t\u01b0\u01a1ng th\u00edch h\u1ec7 th\u1ed1ng (SST – System Suitability Test) l\u00e0 m\u1ed9t x\u00e9t nghi\u1ec7m \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o t\u00ednh ph\u00f9 h\u1ee3p v\u00e0 ho\u1ea1t \u0111\u1ed9ng \u1ed5n \u0111\u1ecbnh c\u1ee7a thi\u1ebft b\u1ecb trong m\u1ed9t \u0111i\u1ec1u ki\u1ec7n m\u00f4i tr\u01b0\u1eddng, v\u1ecb tr\u00ed, v\u00e0 con ng\u01b0\u1eddi nh\u1ea5t \u0111\u1ecbnh. Theo D\u01b0\u1ee3c \u0111i\u1ec3n Hoa K\u1ef3 (USP) v\u00e0 D\u01b0\u1ee3c \u0111i\u1ec3n Ch\u00e2u \u00c2u (EP), c\u00e1c ch\u1ea5t chu\u1ea9n cho ki\u1ec3m tra SST bao g\u1ed3m 1,4-Benzoquinone as 500 ppb C (ch\u1ea5t kh\u00f3 Oxi h\u00f3a) v\u00e0 Sucrose as 500 ppb C (ch\u1ea5t d\u1ec5 oxi h\u00f3a). Trong khi \u0111\u00f3, theo D\u01b0\u1ee3c \u0111i\u1ec3n Nh\u1eadt B\u1ea3n (IP), ch\u1ec9 s\u1eed d\u1ee5ng ch\u1ea5t chu\u1ea9n SDBS (Sodium Dodecyl Benzene Sulfonate) as 500 ppb C cho ki\u1ec3m tra SST.<\/p>\n

Chu\u1ea9n b\u1ecb Dung d\u1ecbch t\u01b0\u01a1ng th\u00edch h\u1ec7 th\u1ed1ng g\u1ed1c<\/strong>: C\u00e2n ch\u00ednh x\u00e1c 75,0 mg ch\u1ea5t chu\u1ea9n 1,4-benzoquinon cho v\u00e0o b\u00ecnh \u0111\u1ecbnh m\u1ee9c 200,0 ml, h\u00f2a tan v\u00e0 pha lo\u00e3ng \u0111\u1ebfn th\u1ec3 t\u00edch b\u1eb1ng n\u01b0\u1edbc th\u1eed, tr\u1ed9n \u0111\u1ec1u.<\/p>\n

    \n
  1. Dung d\u1ecbch t\u01b0\u01a1ng th\u00edch h\u1ec7 th\u1ed1ng: H\u00fat ch\u00ednh x\u00e1c 2,0 ml dung d\u1ecbch t\u01b0\u01a1ng th\u00edch h\u1ec7 th\u1ed1ng g\u1ed1c cho v\u00e0o b\u00ecnh \u0111\u1ecbnh m\u1ee9c 100,0 ml, th\u00eam n\u01b0\u1edbc th\u1eed \u0111\u1ebfn th\u1ec3 t\u00edch v\u00e0 tr\u1ed9n \u0111\u1ec1u. Pha lo\u00e3ng ch\u00ednh x\u00e1c 5,0 ml dung d\u1ecbch n\u00e0y th\u00e0nh 50,0 ml b\u1eb1ng n\u01b0\u1edbc th\u1eed, tr\u1ed9n \u0111\u1ec1u. (Dung d\u1ecbch c\u00f3 n\u1ed3ng \u0111\u1ed9 0,75 mg\/l 1,4-benzoquinon t\u01b0\u01a1ng \u0111\u01b0\u01a1ng 0,50 mg\/l carbon).<\/li>\n
  2. Dung d\u1ecbch chu\u1ea9n: C\u00e2n ch\u00ednh x\u00e1c 149,0 mg ch\u1ea5t chu\u1ea9n sucrose cho v\u00e0o b\u00ecnh \u0111\u1ecbnh m\u1ee9c 500,0 ml, h\u00f2a tan v\u00e0 pha lo\u00e3ng \u0111\u1ebfn th\u1ec3 t\u00edch b\u1eb1ng n\u01b0\u1edbc th\u1eed, tr\u1ed9n \u0111\u1ec1u. Pha lo\u00e3ng ch\u00ednh x\u00e1c 1,0 ml dung d\u1ecbch n\u00e0y th\u00e0nh 250,0 ml b\u1eb1ng n\u01b0\u1edbc th\u1eed, tr\u1ed9n \u0111\u1ec1u. (Dung d\u1ecbch c\u00f3 n\u1ed3ng \u0111\u1ed9 1,19 mg\/l sucrose t\u01b0\u01a1ng \u0111\u01b0\u01a1ng 0,50 mg\/l carbon).<\/li>\n
  3. Dung d\u1ecbch tr\u1eafng: S\u1eed d\u1ee5ng n\u01b0\u1edbc th\u1eed t\u1ea1i c\u00f9ng th\u1eddi \u0111i\u1ec3m pha dung d\u1ecbch t\u01b0\u01a1ng th\u00edch h\u1ec7 th\u1ed1ng v\u00e0 dung d\u1ecbch chu\u1ea9n.<\/li>\n<\/ol>\n

    Tuy nhi\u00ean, \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o \u0111\u1ed9 ch\u00ednh x\u00e1c v\u00e0 ti\u1ec7n l\u1ee3i trong hi\u1ec7u chu\u1ea9n TOC, c\u00e1c ph\u00f2ng QC th\u01b0\u1eddng s\u1eed d\u1ee5ng b\u1ed9 k\u00edt pha s\u1eb3n t\u1eeb c\u00e1c h\u00e3ng s\u1ea3n xu\u1ea5t ch\u1ea5t chu\u1ea9n, v\u1eadt t\u01b0 ti\u00eau hao m\u00e1y TOC chuy\u00ean nghi\u1ec7p (nh\u01b0 h\u00e3ng Altus \u2013 Anh).<\/p>\n

    B\u1ed9 ch\u1ea5t chu\u1ea9n th\u1ef1c hi\u1ec7n SST (System Suitability Kit) bao g\u1ed3m 3 \u1ed1ng vial (th\u1ec3 t\u00edch 40ml): (1) USP Reagent Water Rw, (1) 0.500mg\/L C from USP Sucrose Rs, (1) 0.500mg\/L C from USP 1,4 Benzoquinone Rss.<\/p>\n

    Khi n\u00e0o c\u1ea7n th\u1ef1c hi\u1ec7n SST?<\/strong><\/p>\n

    T\u1ea7n su\u1ea5t th\u1ef1c hi\u1ec7n SST ph\u1ee5 thu\u1ed9c v\u00e0o ti\u00eau chu\u1ea9n n\u1ed9i b\u1ed9 c\u1ee7a nh\u00e0 m\u00e1y s\u1ea3n xu\u1ea5t. Th\u00ed d\u1ee5: nh\u00e0 m\u00e1y Rhoto th\u1ef1c hi\u1ec7n 15 ng\u00e0y\/ l\u1ea7n. Nh\u01b0ng c\u00e1c nh\u00e0 m\u00e1y kh\u00e1c th\u1ef1c hi\u1ec7n 12 th\u00e1ng\/ l\u1ea7n ho\u1eb7c 6 th\u00e1ng\/ l\u1ea7n.<\/p>\n","protected":false},"featured_media":5898,"parent":0,"template":"","meta":{"_acf_changed":false},"class_list":["post-4403","service","type-service","status-publish","has-post-thumbnail","hentry","service-category-huong-dan-quan-ly-thiet-bi"],"acf":[],"yoast_head":"\n\u0110\u00e1nh Gi\u00e1 \u0110\u1ed9 T\u01b0\u01a1ng Th\u00edch H\u1ec7 Th\u1ed1ng TOC (SST) L\u00e0 G\u00ec? 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