MSCs release EVs such as exosomes and microvesicles, which mediate cell-to-cell communication and reflect many of the therapeutic effects of MSCs themselves. Compared with cell-based treatments, EVs may be a more feasible and realistic approach.
Source:
Hu JC, Zheng CX, Sui BD, Liu WJ, Jin Y. Mesenchymal stem cell-derived exosomes: A novel and potential remedy for cutaneous wound healing and regeneration. World J Stem Cells. 2022 May 26;14(5):318-329. doi: 10.4252/wjsc.v14.i5.318. PMID: 35722196; PMCID: PMC9157601.
Roszkowski S. Therapeutic potential of mesenchymal stem cell-derived exosomes for regenerative medicine applications. Clin Exp Med. 2024 Mar 1;24(1):46. doi: 10.1007/s10238-023-01282-z. PMID: 38427086; PMCID: PMC10907468.