CryoStore™ & PermaLife® – Trusted global solutions for CAR-T cells

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ToggleWhy OriGen’s products are critical in CAR-T therapy
In CAR-T therapy, every step – from cell collection, processing, expansion, packaging, to transportation – demands absolute precision. A single error can compromise cell viability and affect treatment outcomes.
That’s why leading medical centers and pharmaceutical companies worldwide trust CryoStore™ and PermaLife® from OriGen Biomedical – GMP-compliant solutions designed to ensure the integrity and viability of CAR-T cells throughout the entire vein-to-vein process.
>> See Origen Biomedical’s introduction article
Origen Biomedical trusted by leading CAR-T centers around the world
Client (Organization) | Country | OriGen products | Application in CAR-T therapy | Key highlights |
Baylor College of Medicine & Texas Children’s Hospital | USA | CryoStore™ Freezing Bag |
Post-manufacturing cold storage and transport of CAR-T infusion products
|
A 2021 study across three academic CAR-T centers (including Baylor) showed that 100% used OriGen’s CryoStore™ bags for infusion products, citing their sealed design and safety compliance. |
Dana-Farber Cancer Institute | USA | CryoStore™ Freezing Bag | Cryopreservation of CAR-T cells after expansion, pre-infusion | Dana-Farber selected CryoStore™ as the standard CAR-T freezing bag, ensuring T cell viability and integrity from manufacturing to infusion. |
M Health Fairview / University of Minnesota | USA | CryoStore™ Freezing Bag | On-site freezing and transport of CAR-T cells | Used CryoStore™ for local CAR-T production. Studies report consistent use of CryoStore™ across multiple U.S. centers due to its proven performance. |
Kite Pharma (Yescarta®) | USA | CryoStore™ Freezing Bag | Commercial-scale packaging and cryopreservation of CAR-T products | Each Yescarta (axicabtagene ciloleucel) dose is frozen in CryoStore™ for global distribution at ≤ –150°C, preserving cell viability during ultra-cold CAR-T transport. |
Novartis (Kymriah®) | Switzerland / Global | CryoStore™ + CryoPur® | Cryopreservation of Kymriah (tisagenlecleucel) post-production and shipping | As the first FDA-approved CAR-T therapy, Kymriah is frozen in CryoStore™ with CryoPur® DMSO-based cryomedia for safe shipment, enabling global delivery while maintaining GMP standards. |
Bristol Myers Squibb (Abecma®) | USA / Global | CryoStore™ Freezing Bag | Frozen storage of CAR-T product Abecma (ide-cel) before infusion | Each Abecma dose (260–500×10^6 cells) is shipped in 1–3 EVA CryoStore™ bags. The durable bag design ensures cell viability and thawing safety during commercial delivery. |
Guy’s Cancer Centre – King’s College London | UK | PermaLife® PL240, PL325, PL70 | Gas-permeable culture bags for T-cell activation and gene transfer | Used for RetroNectin®-coated culture and viral transduction, allowing efficient gene modification without centrifugation. Closed-system GMP setup supports sterility and process consistency. |
Telethon Kids Institute | Australia | CryoStore™ Freezing Bag | Cryopreservation of gene-modified T cells in preclinical CAR-T research | 500 ml CryoStore™ bags used for vapor-phase liquid nitrogen storage (–160°C), with proven functional retention of CAR-T cells after thaw. |
Why do leading CAR-T centers choose OriGen?
Maximized Cell Performance – Viability Preserved to the Final Step
CryoStore™ enables ultra-cold preservation at ≤ –150°C, safeguarding biological activity during shipping. PermaLife® bags enhance gene transfer efficiency without centrifugation, reducing steps and minimizing risks.
Closed-system design – GMP-compliant safety
All bags feature sealed Luer lock ports, which are ideal for aseptic conditions and minimizing contamination, ensuring robust process integrity.
Proven quality – Trusted by the biggest names in CAR-T
OriGen’s products are the standard for global CAR-T packaging in FDA-approved therapies like Yescarta®, Kymriah®, and Abecma®.
Biogroup Vietnam – Your trusted CAR-T partner
As the official distribution partner of OriGen Biomedical in Vietnam, Biogroup Vietnam offers more than just products — we provide end-to-end support:
- Technical consultation to select the proper CAR-T storage and culture solution
- Training, documentation (IFU, COA), and quality certification
-
Proper cold-chain delivery for cell preservation
Ready to optimize your CAR-T workflow?
Let CryoStore™ and PermaLife® help you boost efficiency, reduce risks, and confidently scale your CAR-T therapy today.
Learn more at: https://biogroupvietnam.com/public/
Contact our expert team:
- Email: info@biogroupvietnam.com
- Website: https://biogroupvietnam.com/contact-us
References
1. OriGen Biomedical. (n.d.). CryoStore™ Freezing Bag product information. Retrieved from https://www.origen.com
2. OriGen Biomedical. (n.d.). PermaLife® Cell Culture Bags product guide. Retrieved from https://www.origen.com
3. U.S. National Library of Medicine. (n.d.). PMC – PubMed Central. Retrieved from https://www.ncbi.nlm.nih.gov/pmc
4. Medic Israel. (n.d.). Cryopreservation and transport procedures for Yescarta® (axicabtagene ciloleucel). Retrieved from https://www.medic.co.il
5. BioLife Solutions. (n.d.). Investor updates and cell therapy logistics performance. Retrieved from https://investors.biolifesolutions.com
6. Pink Sheet (Citeline). (2021). Product profile: Abecma® (idecabtagene vicleucel). Retrieved from https://pink.citeline.com
7. University of Western Australia. (n.d.). CAR-T preclinical studies using CryoStore at Telethon Kids Institute. Retrieved from https://research-repository.uwa.edu.au
8. ISCT & ASGCT. (n.d.). Annual conference abstracts and product usage reports. Retrieved from https://www.celltherapysociety.org / https://www.asgct.org
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