CryoStore & PermaLife® - Trusted global solutions for CAR-T cells

New Products & Technologies July 8, 2025

CryoStore and PermaLife® bags for CAR-T cell preservation and culture

Why OriGen’s products are critical in CAR-T therapy

In CAR-T therapy, every step – from cell collection, processing, expansion, packaging, to transportation – demands absolute precision. A single error can compromise cell viability and affect treatment outcomes. That’s why leading medical centers and pharmaceutical companies worldwide trust CryoStore and PermaLife® from OriGen Biomedical – GMP-compliant solutions designed to ensure the integrity and viability of CAR-T cells throughout the entire vein-to-vein process. >> See OriGen Biomedical’s introduction article

OriGen Biomedical trusted by leading CAR-T centers around the world

Client (Organization)CountryOriGen productsApplication in CAR-T therapyKey highlights
Baylor College of Medicine & Texas Children’s HospitalUSACryoStore Freezing BagPost-manufacturing cold storage and transport of CAR-T infusion products A 2021 study across three academic CAR-T centers (including Baylor) showed that 100% used OriGen’s CryoStore bags for infusion products, citing their sealed design and safety compliance.
Dana-Farber Cancer InstituteUSACryoStore Freezing BagCryopreservation of CAR-T cells after expansion, pre-infusionDana-Farber selected CryoStore as the standard CAR-T freezing bag, ensuring T cell viability and integrity from manufacturing to infusion.
M Health Fairview / University of MinnesotaUSACryoStore Freezing BagOn-site freezing and transport of CAR-T cellsUsed CryoStore for local CAR-T production. Studies report consistent use of CryoStore across multiple U.S. centers due to its proven performance.
Kite Pharma (Yescarta®)USACryoStore Freezing BagCommercial-scale packaging and cryopreservation of CAR-T productsEach Yescarta (axicabtagene ciloleucel) dose is frozen in CryoStore for global distribution at ≤ –150°C, preserving cell viability during ultra-cold CAR-T transport.
Novartis (Kymriah®)Switzerland / GlobalCryoStore + CryoPur®Cryopreservation of Kymriah (tisagenlecleucel) post-production and shippingAs the first FDA-approved CAR-T therapy, Kymriah is frozen in CryoStore with CryoPur® DMSO-based cryomedia for safe shipment, enabling global delivery while maintaining GMP standards.
Bristol Myers Squibb (Abecma®)USA / GlobalCryoStore Freezing BagFrozen storage of CAR-T product Abecma (ide-cel) before infusionEach Abecma dose (260–500×10^6 cells) is shipped in 1–3 EVA CryoStore bags. The durable bag design ensures cell viability and thawing safety during commercial delivery.
Guy’s Cancer Centre – King’s College LondonUKPermaLife® PL240, PL325, PL70Gas-permeable culture bags for T-cell activation and gene transferUsed for RetroNectin®-coated culture and viral transduction, allowing efficient gene modification without centrifugation. Closed-system GMP setup supports sterility and process consistency.
Telethon Kids InstituteAustraliaCryoStore Freezing BagCryopreservation of gene-modified T cells in preclinical CAR-T research500 ml CryoStore bags used for vapor-phase liquid nitrogen storage (–160°C), with proven functional retention of CAR-T cells after thaw.

Why do leading CAR-T centers choose OriGen?

Maximized Cell Performance – Viability Preserved to the Final Step

CryoStore enables ultra-cold preservation at ≤ –150°C, safeguarding biological activity during shipping. PermaLife® bags enhance gene transfer efficiency without centrifugation, reducing steps and minimizing risks.

Closed-system design – GMP-compliant safety

All bags feature sealed Luer lock ports, which are ideal for aseptic conditions and minimizing contamination, ensuring robust process integrity.

Proven quality – Trusted by the biggest names in CAR-T

OriGen’s products are the standard for global CAR-T packaging in FDA-approved therapies like Yescarta®, Kymriah®, and Abecma®.

Biogroup Vietnam – Your trusted CAR-T partner

As the official distribution partner of OriGen Biomedical in Vietnam, Biogroup Vietnam offers more than just products — we provide end-to-end support:

  • Technical consultation to select the proper CAR-T storage and culture solution
  • Training, documentation (IFU, COA), and quality certification
  • Proper cold-chain delivery for cell preservation

Ready to optimize your CAR-T workflow? Let CryoStore and PermaLife® help you boost efficiency, reduce risks, and confidently scale your CAR-T therapy today.

Contact our team:

References

1. OriGen Biomedical. (n.d.). CryoStore Freezing Bag product information. Retrieved from https://www.origen.com 2. OriGen Biomedical. (n.d.). PermaLife® Cell Culture Bags product guide. Retrieved from https://www.origen.com 3. U.S. National Library of Medicine. (n.d.). PMC – PubMed Central. Retrieved from https://www.ncbi.nlm.nih.gov/pmc 4. Medic Israel. (n.d.). Cryopreservation and transport procedures for Yescarta® (axicabtagene ciloleucel). Retrieved from https://www.medic.co.il 5. BioLife Solutions. (n.d.). Investor updates and cell therapy logistics performance. Retrieved from https://investors.biolifesolutions.com 6. Pink Sheet (Citeline). (2021). Product profile: Abecma® (idecabtagene vicleucel). Retrieved from https://pink.citeline.com 7. University of Western Australia. (n.d.). CAR-T preclinical studies using CryoStore at Telethon Kids Institute. Retrieved from https://research-repository.uwa.edu.au 8. ISCT & ASGCT. (n.d.). Annual conference abstracts and product usage reports. Retrieved from https://www.celltherapysociety.org / https://www.asgct.org